绿色分析化学的最新应用:用于药物分析的环保方法

IF 3.4 Q2 PHARMACOLOGY & PHARMACY
Meshwa Mehta, Dhara Mehta, Rajashree Mashru
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引用次数: 0

摘要

背景在分析化学领域,主要使用的分析仪器是高效液相色谱法(HPLC)和气相色谱法(GC)等传统方法。由于这些方法使用溶剂、产生垃圾并需要能源,因此严重破坏了自然环境。大量有机溶剂的过度消耗以及由此产生的垃圾会污染环境。因此,研究人员正在创造新颖的绿色分析化学方法,以解决这些环境问题,并创造一种生态上可取的替代品。此外,还可以通过尽可能省略样品制备阶段或使用其他绿色萃取方法来减少对溶剂的需求。采用超高效液相色谱(UHPLC)等紧凑型方法也可减少分析过程中的能源消耗和垃圾产生量。它还提供了有关绿色分析技术应用的信息,如超高压液相色谱法(UHPLC)、高效薄层色谱法(HPTLC)和薄层色谱法(TLC)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recent application of green analytical chemistry: eco-friendly approaches for pharmaceutical analysis

Background

The substantially operated analytical instruments dealing in the area of analytical chemistry are traditional methods like high-performance liquid chromatography (HPLC) and gas chromatography (GC). Since they use solvents, produce trash, and require energy, these methods seriously compromise the natural milieu. The excessive consumption of an enormous number of organic solvents, along with the trash created from it, can contaminate the environment. As a result, researchers are now creating novel Green Analytical Chemistry approaches to address these environmental problems and create an ecologically preferable replacement.

Main body of the abstract

Ecologically preferable replacement can be accomplished by using a green solvent, such as ethanol or water, in place of harmful solvents. Additionally, the need for solvent can be decreased by omitting the sample preparation stage wherever possible or by utilising alternate green extraction methods. Adoption of compact methods like ultra-high-performance liquid chromatography (UHPLC) may also result in a decrease in the amount of energy used and trash produced during analysis.

Short conclusion

This review features information on using sustainable practises in analytical chemistry as well as details on using green solvents and sample preparation methods such as Solid Phase Extraction (SPE), Qucheers. It also provides information related of application of green analytical techniques such UHPLC, High-Performance Thin Layer Chromatography (HPTLC), and Thin Layer Chromatography (TLC).

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来源期刊
自引率
0.00%
发文量
44
审稿时长
23 weeks
期刊介绍: Future Journal of Pharmaceutical Sciences (FJPS) is the official journal of the Future University in Egypt. It is a peer-reviewed, open access journal which publishes original research articles, review articles and case studies on all aspects of pharmaceutical sciences and technologies, pharmacy practice and related clinical aspects, and pharmacy education. The journal publishes articles covering developments in drug absorption and metabolism, pharmacokinetics and dynamics, drug delivery systems, drug targeting and nano-technology. It also covers development of new systems, methods and techniques in pharmacy education and practice. The scope of the journal also extends to cover advancements in toxicology, cell and molecular biology, biomedical research, clinical and pharmaceutical microbiology, pharmaceutical biotechnology, medicinal chemistry, phytochemistry and nutraceuticals.
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