晦涩难懂的 DNA 序列揭示了新的癌症靶点

IF 12.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Structural & Molecular Biology Pub Date : 2024-07-08 DOI:10.1038/s41594-024-01347-x

Agnel Sfeir

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引用次数: 0

摘要

好奇心驱动的基础科学发现必须以其对人类健康的重要性以及实际应用和治疗的转化潜力为依据。然而，许多突破性的发现都是通过自由地提出基本问题--"如何 "和 "为什么"--而产生的，但却不知道这些问题会导致什么结果。这里介绍的是一个临床靶点的例子，它产生于染色体生物学中一个看似简单的问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Obscure DNA sequences unveil a new cancer target

查看原文本刊更多论文

Obscure DNA sequences unveil a new cancer target

Curiosity-driven and fundamental discovery science must be justified in its importance to human health and translational potential for practical applications and cures. However, many groundbreaking discoveries occur through the freedom to ask fundamental questions — the how and why — without knowing where they lead. Presented here is an example of a clinical target that emerged from a seemingly simple question in chromosome biology.

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来源期刊

Nature Structural & Molecular Biology BIOCHEMISTRY & MOLECULAR BIOLOGY-BIOPHYSICS

CiteScore

22.00

自引率

1.80%

发文量

160

审稿时长

3-8 weeks

期刊介绍： Nature Structural & Molecular Biology is a comprehensive platform that combines structural and molecular research. Our journal focuses on exploring the functional and mechanistic aspects of biological processes, emphasizing how molecular components collaborate to achieve a particular function. While structural data can shed light on these insights, our publication does not require them as a prerequisite.