代谢中枢控制中的神经酰胺。

IF 11.4 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Trends in Endocrinology and Metabolism Pub Date : 2025-01-01 Epub Date: 2024-07-06 DOI:10.1016/j.tem.2024.06.007

Miguel López, Carlos Diéguez, Manuel Tena-Sempere, Ismael González-García

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引用次数: 0

摘要

中枢神经酰胺通过影响下丘脑神经元来调节能量代谢。这使得神经酰胺能够整合瘦素、胃泌素、甲状腺激素或雌二醇等内分泌信号，并调节青春期的中枢控制。在这篇论坛文章中，我们将讨论最近的证据表明，特定的神经酰胺种类和神经元群参与了这些作用。

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Ceramides in the central control of metabolism.

Central ceramides regulate energy metabolism by impacting hypothalamic neurons. This allows ceramides to integrate endocrine signals - such as leptin, ghrelin, thyroid hormones, or estradiol - and to modulate the central control of puberty. In this forum article we discuss recent evidence suggesting that specific ceramide species and neuronal populations are involved in these effects.

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来源期刊

Trends in Endocrinology and Metabolism 医学-内分泌学与代谢

CiteScore

20.10

自引率

0.00%

发文量

审稿时长

82 days

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