{"title":"后天性孤立性眼运动神经麻痹患者的临床表现及其与康复模式的关系--一项观察性研究。","authors":"Disha Agarwal, Nirupama Kasturi, Subashini Kaliaperumal","doi":"10.1080/09273972.2024.2363396","DOIUrl":null,"url":null,"abstract":"<p><p><i>Purpose:</i> To study the clinical spectrum and recovery patterns in patients of acquired isolated ocular motor nerve palsies (OMNPs). <i>Methods:</i> Patients above 5 years of age with various etiologies of OMNPs were included. Demographic and ocular details were recorded, and a squint assessment was performed. Recovery patterns at 3 and 6 months were noted. <i>Results:</i> OMNP was more common in adults, in the order VI > III > IV nerve. Ischemic cause (35%) was followed by idiopathic (26.3%). III nerve palsies were all unilateral, of which all ischemic palsies were pupil-sparing. By 6 months, >50 patients showing complete recovery had ischemic and idiopathic palsies. Smaller baseline deviation correlated with better recovery. <i>Conclusion:</i> Acquired isolated OMNPs are mostly ischemia-related, with >80% of cases fully recovering by 6 months. VI nerve palsy of ischemic or idiopathic etiology and small baseline deviation were associated with self-recovery.</p>","PeriodicalId":51700,"journal":{"name":"Strabismus","volume":" ","pages":"210-216"},"PeriodicalIF":0.8000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical spectrum and its association with recovery patterns in patients with acquired isolated ocular motor nerve palsies - an observational study.\",\"authors\":\"Disha Agarwal, Nirupama Kasturi, Subashini Kaliaperumal\",\"doi\":\"10.1080/09273972.2024.2363396\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>Purpose:</i> To study the clinical spectrum and recovery patterns in patients of acquired isolated ocular motor nerve palsies (OMNPs). <i>Methods:</i> Patients above 5 years of age with various etiologies of OMNPs were included. Demographic and ocular details were recorded, and a squint assessment was performed. Recovery patterns at 3 and 6 months were noted. <i>Results:</i> OMNP was more common in adults, in the order VI > III > IV nerve. Ischemic cause (35%) was followed by idiopathic (26.3%). III nerve palsies were all unilateral, of which all ischemic palsies were pupil-sparing. By 6 months, >50 patients showing complete recovery had ischemic and idiopathic palsies. Smaller baseline deviation correlated with better recovery. <i>Conclusion:</i> Acquired isolated OMNPs are mostly ischemia-related, with >80% of cases fully recovering by 6 months. VI nerve palsy of ischemic or idiopathic etiology and small baseline deviation were associated with self-recovery.</p>\",\"PeriodicalId\":51700,\"journal\":{\"name\":\"Strabismus\",\"volume\":\" \",\"pages\":\"210-216\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Strabismus\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/09273972.2024.2363396\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/7/8 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Strabismus","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/09273972.2024.2363396","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/7/8 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
目的:研究获得性孤立性眼运动神经麻痹(OMNPs)患者的临床表现和恢复模式。方法:纳入不同病因导致的 5 岁以上眼运动神经麻痹患者。记录人口统计学和眼部细节,并进行斜视评估。观察患者 3 个月和 6 个月后的恢复情况。结果显示成人的 OMNP 更常见,顺序为 VI 神经 > III 神经 > IV 神经。缺血性原因(35%)次之,特发性原因(26.3%)再次之。III 神经麻痹均为单侧,其中所有缺血性麻痹均为瞳孔缺失。到 6 个月时,超过 50 名完全康复的患者有缺血性和特发性麻痹。基线偏差越小,康复效果越好。结论:获得性孤立 OMNPs 大多与缺血有关,超过 80% 的病例在 6 个月后完全康复。缺血性或特发性 VI 神经麻痹以及基线偏差较小与自我康复有关。
Clinical spectrum and its association with recovery patterns in patients with acquired isolated ocular motor nerve palsies - an observational study.
Purpose: To study the clinical spectrum and recovery patterns in patients of acquired isolated ocular motor nerve palsies (OMNPs). Methods: Patients above 5 years of age with various etiologies of OMNPs were included. Demographic and ocular details were recorded, and a squint assessment was performed. Recovery patterns at 3 and 6 months were noted. Results: OMNP was more common in adults, in the order VI > III > IV nerve. Ischemic cause (35%) was followed by idiopathic (26.3%). III nerve palsies were all unilateral, of which all ischemic palsies were pupil-sparing. By 6 months, >50 patients showing complete recovery had ischemic and idiopathic palsies. Smaller baseline deviation correlated with better recovery. Conclusion: Acquired isolated OMNPs are mostly ischemia-related, with >80% of cases fully recovering by 6 months. VI nerve palsy of ischemic or idiopathic etiology and small baseline deviation were associated with self-recovery.