{"title":"接受鼻内胰高血糖素使用培训的 1 型糖尿病患儿家长对低血糖的恐惧。","authors":"Alda Troncone , Alessia Piscopo , Angela Zanfardino , Antonietta Chianese , Crescenzo Cascella , Gaetana Affuso , Anna Borriello , Stefano Curto , Assunta Serena Rollato , Veronica Testa , Emanuele Miraglia del Giudice , Lorenza Magliano , Dario Iafusco","doi":"10.1016/j.jpsychores.2024.111856","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>To investigate fear of hypoglycemia (FoH) in parents of children with type 1 diabetes (T1D) before and after undergoing training to learn intranasal (IN) glucagon administration.</p></div><div><h3>Method</h3><p>In this pre-test/post-test uncontrolled study 364 caregivers of patients with T1D (6–18 years) completed questionnaires measuring sociodemographic characteristics, diabetes-related factors (e.g., type of insulin therapy, glycemic control), and parents' trait anxiety. Parents' FoH was assessed at baseline (T0, training) and after nine months (T1). Two repeated-measure mixed analyses of covariance (ANCOVA) compared the FoH at T0 and at T1 and analyzed the moderating roles of anxiety proneness and type of insulin therapy, as well as of anxiety proneness and use of sensor. Age, T1D duration, HbA1c values, and SES were included as covariates.</p></div><div><h3>Results</h3><p>Parental FoH at T1 (M = 1.72; SE = 0.06/M = 1.57; SE = 0.09) was significantly lower than parental FoH at T0 (M = 1.89; SE = 0.06/M = 1.77; SE = 0.09). The group with high trait-anxiety had a higher level of FoH (M = 2.05; SE = 0.08/M = 1.89; SE = 0.12) than the group with low trait-anxiety (M = 1.57; SE = 0.08/M = 1.46; SE = 0.09) at both time points. SES was negatively associated with FoH at T0 (<em>t</em> = −2.87; <em>p =</em> .004/<em>t</em> = −2.87; <em>p</em> = .005). No other significant effects were found.</p></div><div><h3>Conclusions</h3><p>Training and educating parents on IN glucagon use can help them effectively manage hypoglycemic episodes and alleviate the fear that generally accompany such events.</p></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":null,"pages":null},"PeriodicalIF":3.5000,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S002239992400268X/pdfft?md5=d395245850f742bd96e83efbbf3bb01b&pid=1-s2.0-S002239992400268X-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Fear of hypoglycemia in parents of children with type 1 diabetes trained for intranasal glucagon use\",\"authors\":\"Alda Troncone , Alessia Piscopo , Angela Zanfardino , Antonietta Chianese , Crescenzo Cascella , Gaetana Affuso , Anna Borriello , Stefano Curto , Assunta Serena Rollato , Veronica Testa , Emanuele Miraglia del Giudice , Lorenza Magliano , Dario Iafusco\",\"doi\":\"10.1016/j.jpsychores.2024.111856\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>To investigate fear of hypoglycemia (FoH) in parents of children with type 1 diabetes (T1D) before and after undergoing training to learn intranasal (IN) glucagon administration.</p></div><div><h3>Method</h3><p>In this pre-test/post-test uncontrolled study 364 caregivers of patients with T1D (6–18 years) completed questionnaires measuring sociodemographic characteristics, diabetes-related factors (e.g., type of insulin therapy, glycemic control), and parents' trait anxiety. Parents' FoH was assessed at baseline (T0, training) and after nine months (T1). Two repeated-measure mixed analyses of covariance (ANCOVA) compared the FoH at T0 and at T1 and analyzed the moderating roles of anxiety proneness and type of insulin therapy, as well as of anxiety proneness and use of sensor. Age, T1D duration, HbA1c values, and SES were included as covariates.</p></div><div><h3>Results</h3><p>Parental FoH at T1 (M = 1.72; SE = 0.06/M = 1.57; SE = 0.09) was significantly lower than parental FoH at T0 (M = 1.89; SE = 0.06/M = 1.77; SE = 0.09). The group with high trait-anxiety had a higher level of FoH (M = 2.05; SE = 0.08/M = 1.89; SE = 0.12) than the group with low trait-anxiety (M = 1.57; SE = 0.08/M = 1.46; SE = 0.09) at both time points. SES was negatively associated with FoH at T0 (<em>t</em> = −2.87; <em>p =</em> .004/<em>t</em> = −2.87; <em>p</em> = .005). No other significant effects were found.</p></div><div><h3>Conclusions</h3><p>Training and educating parents on IN glucagon use can help them effectively manage hypoglycemic episodes and alleviate the fear that generally accompany such events.</p></div>\",\"PeriodicalId\":50074,\"journal\":{\"name\":\"Journal of Psychosomatic Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2024-07-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S002239992400268X/pdfft?md5=d395245850f742bd96e83efbbf3bb01b&pid=1-s2.0-S002239992400268X-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Psychosomatic Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S002239992400268X\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Psychosomatic Research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S002239992400268X","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
摘要
目的研究1型糖尿病(T1D)患儿家长在接受鼻内注射胰高血糖素(IN)培训前后对低血糖(FoH)的恐惧:在这项前测/后测非对照研究中,364 名 1 型糖尿病患者(6-18 岁)的照顾者填写了调查问卷,调查内容包括社会人口学特征、糖尿病相关因素(如胰岛素治疗类型、血糖控制情况)以及父母的特质焦虑。在基线(T0,培训)和九个月后(T1)对家长的 FoH 进行了评估。两次重复测量混合协方差分析(ANCOVA)比较了 T0 和 T1 时的 FoH,并分析了焦虑倾向和胰岛素治疗类型以及焦虑倾向和传感器使用的调节作用。年龄、T1D持续时间、HbA1c值和社会经济地位被列为协变量:结果:T1时父母的FoH(M = 1.72; SE = 0.06/M = 1.57; SE = 0.09)明显低于T0时父母的FoH(M = 1.89; SE = 0.06/M = 1.77; SE = 0.09)。在两个时间点上,高特质焦虑组的 FoH 水平(M = 2.05;SE = 0.08/M = 1.89;SE = 0.12)均高于低特质焦虑组(M = 1.57;SE = 0.08/M = 1.46;SE = 0.09)。在 T0 阶段,SES 与 FoH 呈负相关(t = -2.87; p = .004/t = -2.87; p = .005)。没有发现其他重大影响:结论:对家长进行 IN 胰高血糖素使用方面的培训和教育可帮助他们有效控制低血糖发作,并减轻低血糖发生时家长的恐惧心理。
Fear of hypoglycemia in parents of children with type 1 diabetes trained for intranasal glucagon use
Objective
To investigate fear of hypoglycemia (FoH) in parents of children with type 1 diabetes (T1D) before and after undergoing training to learn intranasal (IN) glucagon administration.
Method
In this pre-test/post-test uncontrolled study 364 caregivers of patients with T1D (6–18 years) completed questionnaires measuring sociodemographic characteristics, diabetes-related factors (e.g., type of insulin therapy, glycemic control), and parents' trait anxiety. Parents' FoH was assessed at baseline (T0, training) and after nine months (T1). Two repeated-measure mixed analyses of covariance (ANCOVA) compared the FoH at T0 and at T1 and analyzed the moderating roles of anxiety proneness and type of insulin therapy, as well as of anxiety proneness and use of sensor. Age, T1D duration, HbA1c values, and SES were included as covariates.
Results
Parental FoH at T1 (M = 1.72; SE = 0.06/M = 1.57; SE = 0.09) was significantly lower than parental FoH at T0 (M = 1.89; SE = 0.06/M = 1.77; SE = 0.09). The group with high trait-anxiety had a higher level of FoH (M = 2.05; SE = 0.08/M = 1.89; SE = 0.12) than the group with low trait-anxiety (M = 1.57; SE = 0.08/M = 1.46; SE = 0.09) at both time points. SES was negatively associated with FoH at T0 (t = −2.87; p = .004/t = −2.87; p = .005). No other significant effects were found.
Conclusions
Training and educating parents on IN glucagon use can help them effectively manage hypoglycemic episodes and alleviate the fear that generally accompany such events.
期刊介绍:
The Journal of Psychosomatic Research is a multidisciplinary research journal covering all aspects of the relationships between psychology and medicine. The scope is broad and ranges from basic human biological and psychological research to evaluations of treatment and services. Papers will normally be concerned with illness or patients rather than studies of healthy populations. Studies concerning special populations, such as the elderly and children and adolescents, are welcome. In addition to peer-reviewed original papers, the journal publishes editorials, reviews, and other papers related to the journal''s aims.