镰状细胞病中的羟基脲与侵袭性细菌感染：一项病例对照研究。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2024-09-26 DOI:10.1093/jpids/piae071

Alice Pascault, Bérengère Koehl, Valentine Brousse, Malika Benkerrou, Jean Gaschignard

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引用次数: 0

摘要

羟基脲可减少镰状细胞病患儿的疼痛，但会因白细胞减少而增加患者感染的风险。我们进行了一项病例对照研究，比较了使用羟基脲治疗镰状细胞病时感染侵入性细菌的病例和未感染的对照组。结果未发现差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Hydroxyurea in Sickle Cell Disease and Invasive Bacterial Infections: A Case-Control Study.

Hydroxyurea decreases painful events among children with sickle cell disease (SCD) but could increase the risk of infections in treated patients through leucopenia. We performed a case-control study, comparing hydroxyurea treatment for SCD in cases with an invasive bacterial infection and in controls without infection. No difference was found.

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464