{"title":"关于 \"挖掘微藻虾青素这种超级抗氧化剂对口腔癌及相关疾病的治疗潜力 \"的评论","authors":"Antonyraj Matharasi Perianaika Anahas, Ganapathy Dhanraj","doi":"10.1016/j.oor.2024.100571","DOIUrl":null,"url":null,"abstract":"<div><p>Oral cancer treatment potentially advances with the application of C-phycocyanin (C-PC), a powerful antioxidant produced by cyanobacteria. By triggering mechanisms that impair the metabolism of mitochondria and cause cancer cells to initiate apoptosis, this pigment demonstrates potent apoptotic-inducing potentials. Innovative application for C-PC includes integrating it with fibrous scaffolds for long-term release, stimulating tissue regeneration, and lowering inflammation and oxidative damage after surgery. Surgical implants with C-PC, such stents and sutures, provide focused therapy at the locations of oral cancer. In order to enhance the therapeutic uses of C-PC in oral cancer, further studies may investigate genetically modified microalgae. Validating these therapeutic effects and advancing cyanobacterial pigment-based drugs into clinical applications demand further studies.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004175/pdfft?md5=b86cc38af07f9988a9c4308f83abc51e&pid=1-s2.0-S2772906024004175-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Comment on “Unlocking the therapeutic potential of microalgal astaxanthin a super antioxidant in oral cancer and associated ailments”\",\"authors\":\"Antonyraj Matharasi Perianaika Anahas, Ganapathy Dhanraj\",\"doi\":\"10.1016/j.oor.2024.100571\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Oral cancer treatment potentially advances with the application of C-phycocyanin (C-PC), a powerful antioxidant produced by cyanobacteria. By triggering mechanisms that impair the metabolism of mitochondria and cause cancer cells to initiate apoptosis, this pigment demonstrates potent apoptotic-inducing potentials. Innovative application for C-PC includes integrating it with fibrous scaffolds for long-term release, stimulating tissue regeneration, and lowering inflammation and oxidative damage after surgery. Surgical implants with C-PC, such stents and sutures, provide focused therapy at the locations of oral cancer. In order to enhance the therapeutic uses of C-PC in oral cancer, further studies may investigate genetically modified microalgae. Validating these therapeutic effects and advancing cyanobacterial pigment-based drugs into clinical applications demand further studies.</p></div>\",\"PeriodicalId\":94378,\"journal\":{\"name\":\"Oral Oncology Reports\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2772906024004175/pdfft?md5=b86cc38af07f9988a9c4308f83abc51e&pid=1-s2.0-S2772906024004175-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oral Oncology Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772906024004175\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Oncology Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772906024004175","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Comment on “Unlocking the therapeutic potential of microalgal astaxanthin a super antioxidant in oral cancer and associated ailments”
Oral cancer treatment potentially advances with the application of C-phycocyanin (C-PC), a powerful antioxidant produced by cyanobacteria. By triggering mechanisms that impair the metabolism of mitochondria and cause cancer cells to initiate apoptosis, this pigment demonstrates potent apoptotic-inducing potentials. Innovative application for C-PC includes integrating it with fibrous scaffolds for long-term release, stimulating tissue regeneration, and lowering inflammation and oxidative damage after surgery. Surgical implants with C-PC, such stents and sutures, provide focused therapy at the locations of oral cancer. In order to enhance the therapeutic uses of C-PC in oral cancer, further studies may investigate genetically modified microalgae. Validating these therapeutic effects and advancing cyanobacterial pigment-based drugs into clinical applications demand further studies.