Junyan Ma , Mingtao Zhao , Chi Qin , Xiangtao Kong , Hua Xie , Xianshuo Zhang , Zilin Jiao , Zhenxing Zhang
{"title":"用于检测生物系统中亚硫酸氢盐和粘度的抗氧化荧光探针","authors":"Junyan Ma , Mingtao Zhao , Chi Qin , Xiangtao Kong , Hua Xie , Xianshuo Zhang , Zilin Jiao , Zhenxing Zhang","doi":"10.1016/j.dyepig.2024.112321","DOIUrl":null,"url":null,"abstract":"<div><p>Fluorescence probes bearing malononitrile derivatives as electron withdrawing group have attracted the interests of many researchers during the past decades. Even for the similar fluorophore, the sensing mechanism and pathway could be much different and hard to predict. Thus, we designed a fluorescence probe consisting 2-(3,5,5-trimethylcyclohex-2-en-1-ylidene)malononitrile as the electron withdrawing group and thienocoumarin as fluorophore in order to investigate the possible superiority in designing related optical sensors. In our research, it is interesting to find that our probe has the different properties compared with the similar reported probe bearing the coumarin fluorophore. The novel fluorescent probe (<strong>CSO–CN</strong>) was demonstrated to be able to detect HSO<sub>3</sub><sup>−</sup> ions and changes in viscosity with a good resistance to oxidizers. The probe offers high sensitivity (LOD = 0.149 μM) for detecting HSO<sub>3</sub><sup>−</sup> via the Michael addition reaction. It also enables fluorescence emission at 483 nm and the tracking of viscosity alternation by impeding the twisted intramolecular charge transfer (TICT) mechanism. Besides, the dual-functional probe has effectively been utilized to monitor HSO<sub>3</sub><sup>−</sup> level in living cells, zebrafish and real food samples.</p></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":null,"pages":null},"PeriodicalIF":4.1000,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An oxidizer-resistant fluorescence probe for detecting bisulfite and viscosity in biosystems\",\"authors\":\"Junyan Ma , Mingtao Zhao , Chi Qin , Xiangtao Kong , Hua Xie , Xianshuo Zhang , Zilin Jiao , Zhenxing Zhang\",\"doi\":\"10.1016/j.dyepig.2024.112321\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Fluorescence probes bearing malononitrile derivatives as electron withdrawing group have attracted the interests of many researchers during the past decades. Even for the similar fluorophore, the sensing mechanism and pathway could be much different and hard to predict. Thus, we designed a fluorescence probe consisting 2-(3,5,5-trimethylcyclohex-2-en-1-ylidene)malononitrile as the electron withdrawing group and thienocoumarin as fluorophore in order to investigate the possible superiority in designing related optical sensors. In our research, it is interesting to find that our probe has the different properties compared with the similar reported probe bearing the coumarin fluorophore. The novel fluorescent probe (<strong>CSO–CN</strong>) was demonstrated to be able to detect HSO<sub>3</sub><sup>−</sup> ions and changes in viscosity with a good resistance to oxidizers. The probe offers high sensitivity (LOD = 0.149 μM) for detecting HSO<sub>3</sub><sup>−</sup> via the Michael addition reaction. It also enables fluorescence emission at 483 nm and the tracking of viscosity alternation by impeding the twisted intramolecular charge transfer (TICT) mechanism. Besides, the dual-functional probe has effectively been utilized to monitor HSO<sub>3</sub><sup>−</sup> level in living cells, zebrafish and real food samples.</p></div>\",\"PeriodicalId\":302,\"journal\":{\"name\":\"Dyes and Pigments\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2024-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dyes and Pigments\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0143720824003863\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dyes and Pigments","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0143720824003863","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
An oxidizer-resistant fluorescence probe for detecting bisulfite and viscosity in biosystems
Fluorescence probes bearing malononitrile derivatives as electron withdrawing group have attracted the interests of many researchers during the past decades. Even for the similar fluorophore, the sensing mechanism and pathway could be much different and hard to predict. Thus, we designed a fluorescence probe consisting 2-(3,5,5-trimethylcyclohex-2-en-1-ylidene)malononitrile as the electron withdrawing group and thienocoumarin as fluorophore in order to investigate the possible superiority in designing related optical sensors. In our research, it is interesting to find that our probe has the different properties compared with the similar reported probe bearing the coumarin fluorophore. The novel fluorescent probe (CSO–CN) was demonstrated to be able to detect HSO3− ions and changes in viscosity with a good resistance to oxidizers. The probe offers high sensitivity (LOD = 0.149 μM) for detecting HSO3− via the Michael addition reaction. It also enables fluorescence emission at 483 nm and the tracking of viscosity alternation by impeding the twisted intramolecular charge transfer (TICT) mechanism. Besides, the dual-functional probe has effectively been utilized to monitor HSO3− level in living cells, zebrafish and real food samples.
期刊介绍:
Dyes and Pigments covers the scientific and technical aspects of the chemistry and physics of dyes, pigments and their intermediates. Emphasis is placed on the properties of the colouring matters themselves rather than on their applications or the system in which they may be applied.
Thus the journal accepts research and review papers on the synthesis of dyes, pigments and intermediates, their physical or chemical properties, e.g. spectroscopic, surface, solution or solid state characteristics, the physical aspects of their preparation, e.g. precipitation, nucleation and growth, crystal formation, liquid crystalline characteristics, their photochemical, ecological or biological properties and the relationship between colour and chemical constitution. However, papers are considered which deal with the more fundamental aspects of colourant application and of the interactions of colourants with substrates or media.
The journal will interest a wide variety of workers in a range of disciplines whose work involves dyes, pigments and their intermediates, and provides a platform for investigators with common interests but diverse fields of activity such as cosmetics, reprographics, dye and pigment synthesis, medical research, polymers, etc.