Runjie Li , Xiaoyan Chen , Huiyu Tang , Shuyue Luo , Rongna Lian , Wenyi Zhang , Xiangyu Zhang , Xiaoyi Hu , Ming Yang
{"title":"肌肉松弛性肥胖与老年人跌倒：中国西部社区ESPEN/EASO标准及修改的验证研究。","authors":"Runjie Li , Xiaoyan Chen , Huiyu Tang , Shuyue Luo , Rongna Lian , Wenyi Zhang , Xiangyu Zhang , Xiaoyi Hu , Ming Yang","doi":"10.1016/j.archger.2024.105557","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><p>The ESPEN and the EASO recently developed consensus criteria for sarcopenic obesity (SO), employing the skeletal muscle mass to weight (SMM/W) ratio. Emerging evidence suggests that adjusting skeletal muscle mass for body mass index (SMM/BMI) could enhance the predictive accuracy for health outcomes. We aimed to validate the ESPEN/EASO criteria and explore the potential benefits of the SMM/BMI adjustment in predicting falls among older adults in Western China.</p></div><div><h3>Methods</h3><p>We conducted a multicenter, cross-sectional study and included community-dwelling older adults. The diagnosis of SO was determined using the standard ESPEN/EASO consensus criteria (SO<sub>ESPEN</sub>) and a modified version adjusting SMM/BMI (SO<sub>ESPEN-M</sub>). The associations of SO<sub>ESPEN</sub>, SO<sub>ESPEN-M</sub>, and their components with falls were analyzed.</p></div><div><h3>Results</h3><p>Among the 1353 participants, the prevalence of SO was 13.2 % (SO<sub>ESPEN</sub>) and 11.4 % (SO<sub>ESPEN-M</sub>), which increased with age and higher BMI levels. Within participants with a normal BMI, 4.2 % and 6.2 % were found to have SO<sub>ESPEN</sub> and SO<sub>ESPEN-M</sub>, respectively. SMM/W and SMM/BMI negatively correlated with fall risk (<em>p</em>=0.042 and <em>p</em>=0.021, respectively). Upon adjusting for confounders, only SO<sub>ESPEN</sub> was significantly associated with falls (odds ratios [OR] 1.61, 95 % confidence interval [CI] 1.08 to 2.40), whereas the association for SO<sub>ESPEN-M</sub> did not achieve significance (OR 1.55, 95 % CI 0.99 to 2.43).</p></div><div><h3>Conclusions</h3><p>This research validated the ESPEN/EASO criteria (SO<sub>ESPEN</sub>) and their modified version (SO<sub>ESPEN-M</sub>) among community-dwelling older adults in Western China. The SMM/BMI adjustment appears to offer a lower estimate of SO prevalence, with only SO<sub>ESPEN</sub> showing a significant association with falls.</p></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"127 ","pages":"Article 105557"},"PeriodicalIF":3.5000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sarcopenic obesity and falls in older adults: A validation study of ESPEN/EASO criteria and modifications in Western China communities\",\"authors\":\"Runjie Li , Xiaoyan Chen , Huiyu Tang , Shuyue Luo , Rongna Lian , Wenyi Zhang , Xiangyu Zhang , Xiaoyi Hu , Ming Yang\",\"doi\":\"10.1016/j.archger.2024.105557\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><p>The ESPEN and the EASO recently developed consensus criteria for sarcopenic obesity (SO), employing the skeletal muscle mass to weight (SMM/W) ratio. Emerging evidence suggests that adjusting skeletal muscle mass for body mass index (SMM/BMI) could enhance the predictive accuracy for health outcomes. We aimed to validate the ESPEN/EASO criteria and explore the potential benefits of the SMM/BMI adjustment in predicting falls among older adults in Western China.</p></div><div><h3>Methods</h3><p>We conducted a multicenter, cross-sectional study and included community-dwelling older adults. The diagnosis of SO was determined using the standard ESPEN/EASO consensus criteria (SO<sub>ESPEN</sub>) and a modified version adjusting SMM/BMI (SO<sub>ESPEN-M</sub>). The associations of SO<sub>ESPEN</sub>, SO<sub>ESPEN-M</sub>, and their components with falls were analyzed.</p></div><div><h3>Results</h3><p>Among the 1353 participants, the prevalence of SO was 13.2 % (SO<sub>ESPEN</sub>) and 11.4 % (SO<sub>ESPEN-M</sub>), which increased with age and higher BMI levels. Within participants with a normal BMI, 4.2 % and 6.2 % were found to have SO<sub>ESPEN</sub> and SO<sub>ESPEN-M</sub>, respectively. SMM/W and SMM/BMI negatively correlated with fall risk (<em>p</em>=0.042 and <em>p</em>=0.021, respectively). Upon adjusting for confounders, only SO<sub>ESPEN</sub> was significantly associated with falls (odds ratios [OR] 1.61, 95 % confidence interval [CI] 1.08 to 2.40), whereas the association for SO<sub>ESPEN-M</sub> did not achieve significance (OR 1.55, 95 % CI 0.99 to 2.43).</p></div><div><h3>Conclusions</h3><p>This research validated the ESPEN/EASO criteria (SO<sub>ESPEN</sub>) and their modified version (SO<sub>ESPEN-M</sub>) among community-dwelling older adults in Western China. The SMM/BMI adjustment appears to offer a lower estimate of SO prevalence, with only SO<sub>ESPEN</sub> showing a significant association with falls.</p></div>\",\"PeriodicalId\":8306,\"journal\":{\"name\":\"Archives of gerontology and geriatrics\",\"volume\":\"127 \",\"pages\":\"Article 105557\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2024-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of gerontology and geriatrics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0167494324002334\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"GERIATRICS & GERONTOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of gerontology and geriatrics","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0167494324002334","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GERIATRICS & GERONTOLOGY","Score":null,"Total":0}
Sarcopenic obesity and falls in older adults: A validation study of ESPEN/EASO criteria and modifications in Western China communities
Objectives
The ESPEN and the EASO recently developed consensus criteria for sarcopenic obesity (SO), employing the skeletal muscle mass to weight (SMM/W) ratio. Emerging evidence suggests that adjusting skeletal muscle mass for body mass index (SMM/BMI) could enhance the predictive accuracy for health outcomes. We aimed to validate the ESPEN/EASO criteria and explore the potential benefits of the SMM/BMI adjustment in predicting falls among older adults in Western China.
Methods
We conducted a multicenter, cross-sectional study and included community-dwelling older adults. The diagnosis of SO was determined using the standard ESPEN/EASO consensus criteria (SOESPEN) and a modified version adjusting SMM/BMI (SOESPEN-M). The associations of SOESPEN, SOESPEN-M, and their components with falls were analyzed.
Results
Among the 1353 participants, the prevalence of SO was 13.2 % (SOESPEN) and 11.4 % (SOESPEN-M), which increased with age and higher BMI levels. Within participants with a normal BMI, 4.2 % and 6.2 % were found to have SOESPEN and SOESPEN-M, respectively. SMM/W and SMM/BMI negatively correlated with fall risk (p=0.042 and p=0.021, respectively). Upon adjusting for confounders, only SOESPEN was significantly associated with falls (odds ratios [OR] 1.61, 95 % confidence interval [CI] 1.08 to 2.40), whereas the association for SOESPEN-M did not achieve significance (OR 1.55, 95 % CI 0.99 to 2.43).
Conclusions
This research validated the ESPEN/EASO criteria (SOESPEN) and their modified version (SOESPEN-M) among community-dwelling older adults in Western China. The SMM/BMI adjustment appears to offer a lower estimate of SO prevalence, with only SOESPEN showing a significant association with falls.
期刊介绍：
Archives of Gerontology and Geriatrics provides a medium for the publication of papers from the fields of experimental gerontology and clinical and social geriatrics. The principal aim of the journal is to facilitate the exchange of information between specialists in these three fields of gerontological research. Experimental papers dealing with the basic mechanisms of aging at molecular, cellular, tissue or organ levels will be published.
Clinical papers will be accepted if they provide sufficiently new information or are of fundamental importance for the knowledge of human aging. Purely descriptive clinical papers will be accepted only if the results permit further interpretation. Papers dealing with anti-aging pharmacological preparations in humans are welcome. Papers on the social aspects of geriatrics will be accepted if they are of general interest regarding the epidemiology of aging and the efficiency and working methods of the social organizations for the health care of the elderly.
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