出生后 28 天内极低出生体重新生儿脑血流速度的标准值。

IF 1.7 4区医学 Q2 PEDIATRICS

Indian pediatrics Pub Date : 2024-09-15 Epub Date: 2024-06-25

Anup Thakur, Parul Jain, Manoj Modi, Anita Singh, Bharat Kansal, Neelam Kler

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引用次数: 0

摘要

目的确定极低出生体重（VLBW）新生儿出生后 28 天内脑血流（CBF）速度的正常值：在这项前瞻性观察研究中，对出生后 2-8小时、24小时、第3天、第7天、第14天和第28天的大脑前动脉（ACA）、大脑中动脉（MCA）和基底动脉（BA）的 CBF 速度进行了多普勒评估。有严重先天性畸形的新生儿、出生时需要大量抢救的新生儿、平均气道压大于 12 毫巴的机械通气新生儿、需要肌注的新生儿或出现脑室内出血（II 级或以上）的新生儿均不包括在内：共有 103 名超低体重新生儿入选，记录了 1178 次多普勒测量。从出生后 2 至 8 小时到第 28 天，ACA 收缩峰值速度、舒张末期速度和平均速度（厘米/秒）的平均值（标清）分别从 26.53（8.56）增至 51.35（9.36）、9.22（2.91）增至 13.9（3.24）和 17.75（3.97）增至 25.84（3.27）。在 MCA 和 BA 中，CBF 速度也随着出生后年龄的增长而增加：我们报告了超低体重新生儿出生后 28 天内的 CBF 流速标准数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Normative Values of Cerebral Blood Flow Velocities in Very Low Birth Weight Neonates During First 28 Days of Life.

Objective: To determine the normative values of cerebral blood flow (CBF) velocities in very low birth weight (VLBW) neonates during the first 28 days of life.

Method: In this prospective observational study, doppler assessment of CBF velocities was performed from the anterior cerebral artery (ACA), middle cerebral artery (MCA) and basilar artery (BA) at 2-8 hours, 24 hours, day 3, 7, 14 and 28 of life. Neonates with gross congenital malformations, those requiring extensive resuscitation at birth, mechanical ventilation with mean airway pressure >12 mbar, requiring inotropes, or those who developed intraventricular hemorrhage (grade II or more) were excluded.

Results: A total of 103 VLBW neonates were enrolled, in whom 1178 doppler measurements were recorded. The mean (SD) peak systolic velocity, end diastolic velocity and mean velocity (cm/s) in ACA increased from 26.53 (8.56) to 51.35 (9.36), 9.22 (2.91) to 13.9 (3.24) and 17.75 (3.97) to 25.84 (3.27) respectively from 2 to 8 hours to day 28 of life. In MCA and BA also, CBF velocities increased with post-natal age.

Conclusion: We report normative data of CBF velocities in VLBW neonates in first 28 days of life.

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来源期刊

Indian pediatrics 医学-小儿科

CiteScore

3.30

自引率

8.70%

发文量

344

审稿时长

3-8 weeks

期刊介绍： The general objective of Indian Pediatrics is "To promote the science and practice of Pediatrics." An important guiding principle has been the simultaneous need to inform, educate and entertain the target audience. The specific key objectives are: -To publish original, relevant, well researched peer reviewed articles on issues related to child health. -To provide continuing education to support informed clinical decisions and research. -To foster responsible and balanced debate on controversial issues that affect child health, including non-clinical areas such as medical education, ethics, law, environment and economics. -To achieve the highest level of ethical medical journalism and to produce a publication that is timely, credible and enjoyable to read.