一种新颖的预脱水猪肝细胞真皮基质:组织学和临床评估

IF 3 Q3 MATERIALS SCIENCE, BIOMATERIALS
International Journal of Biomaterials Pub Date : 2024-06-27 eCollection Date: 2024-01-01 DOI:10.1155/2024/7322223
Andreas van Orten, Werner Goetz, Hakan Bilhan
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引用次数: 0

摘要

众所周知,牙科种植体周围软组织的质量和数量对日后种植体周围的健康至关重要。为此,本病例系列评估了使用新型预水化猪无细胞真皮基质移植体(PPADMG)进行软组织增量以改善软组织并同时植入种植体后,种植体周围粘膜的临床和组织学效果。研究共纳入了 22 名患者。他们接受了晚期种植体植入方案,并结合 PPADMG 进行了软组织增量。在平均 157 天的愈合时间后,在水下愈合的种植体未恢复时进行了打孔活检。在植入种植体和拔出种植体时测量了胸骨上软组织高度(STH)。所有部位的 STH 都出现了临床增长。活组织切片的组织学结构与健康口腔粘膜的结构相似。没有发现意外的组织反应。在这项临床和组织学研究的范围内,可以得出这样的结论:使用这种新型的孔源性非细胞真皮基质,结合同时植入的种植体,可以改善 STH,从而增加种植体周围组织的厚度和稳定性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Novel Prehydrated Porcine-Derived Acellular Dermal Matrix: A Histological and Clinical Evaluation.

It is well known that soft tissue quality and quantity around dental implants is of paramount importance for later peri-implant health. For this purpose, the clinical and histological outcomes of the peri-implant mucosa, following soft tissue augmentation for soft tissue improvement with a novel prehydrated porcine acellular dermal matrix graft (PPADMG) in conjunction with simultaneous implant placement, were evaluated in this case series. Twenty-two patients were included in the study. They underwent a late implant placement protocol combined with PPADMG for soft tissue augmentation. A punch biopsy was taken at the time of uncovery of the submerged healed implant after a mean of 157 days healing time. Supracrestal soft tissue height (STH) was measured at the time of implant placement and uncovery. All sites showed a clinical increase in STH. The histological structure of the biopsies resembled a similar structure as found in the healthy oral mucosa. No unexpected tissue reactions could be found. Within the limits of this clinical and histological study, it may be concluded that STH improvement with this novel porcine-derived acellular dermal matrix, in combination with simultaneous implant placement, is a viable option to create a peri-implant tissue thickness and stability.

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来源期刊
International Journal of Biomaterials
International Journal of Biomaterials MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
4.30
自引率
3.20%
发文量
50
审稿时长
21 weeks
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