{"title":"基于有源块 EX-CCII 的电路，用于 OSCC 的实际阻抗数据","authors":"Bidhanshel Singh Athokpam, Ashish Ranjan, Sumita Banerjee, Vivek Bhatt, Mamata Maisnam, Saikat Mukherjee","doi":"10.1007/s10470-024-02273-0","DOIUrl":null,"url":null,"abstract":"<div><p>Oral Squamous Cell Carcinoma (OSCC) is the most common oral cancer, and its behavior can be analyzed using bio-impedance. A single dispersion Cole model is designed using active block Extra X Current Conveyor (EX-CCII), which generates the existing practical oral OSCC bio-impedance data. An experimental result of cancer bio-impedance in the 20 Hz to 5 MHz range is well modeled with an active block EX-CCII resistors (R <span>\\(_{\\infty }\\)</span> and R<sub>1</sub>) and fractional capacitor (C<sub>α</sub>). The proposed design can serve as a step forward for designing a purposeful method for analyzing the behavior of oral cancer impedance without any practical data. The functionality of the proposed electrical circuit for OSCC is well verified through PSPICE simulation using both 0.25 μm CMOS TSMC Technology parameters and the macro model of EX-CCII. Simulation results agree well with experimental bio-impedance data.</p></div>","PeriodicalId":7827,"journal":{"name":"Analog Integrated Circuits and Signal Processing","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Active block EX-CCII based electrical circuit for practical impedance data of OSCC\",\"authors\":\"Bidhanshel Singh Athokpam, Ashish Ranjan, Sumita Banerjee, Vivek Bhatt, Mamata Maisnam, Saikat Mukherjee\",\"doi\":\"10.1007/s10470-024-02273-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Oral Squamous Cell Carcinoma (OSCC) is the most common oral cancer, and its behavior can be analyzed using bio-impedance. A single dispersion Cole model is designed using active block Extra X Current Conveyor (EX-CCII), which generates the existing practical oral OSCC bio-impedance data. An experimental result of cancer bio-impedance in the 20 Hz to 5 MHz range is well modeled with an active block EX-CCII resistors (R <span>\\\\(_{\\\\infty }\\\\)</span> and R<sub>1</sub>) and fractional capacitor (C<sub>α</sub>). The proposed design can serve as a step forward for designing a purposeful method for analyzing the behavior of oral cancer impedance without any practical data. The functionality of the proposed electrical circuit for OSCC is well verified through PSPICE simulation using both 0.25 μm CMOS TSMC Technology parameters and the macro model of EX-CCII. Simulation results agree well with experimental bio-impedance data.</p></div>\",\"PeriodicalId\":7827,\"journal\":{\"name\":\"Analog Integrated Circuits and Signal Processing\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2024-07-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Analog Integrated Circuits and Signal Processing\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s10470-024-02273-0\",\"RegionNum\":4,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"COMPUTER SCIENCE, HARDWARE & ARCHITECTURE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analog Integrated Circuits and Signal Processing","FirstCategoryId":"5","ListUrlMain":"https://link.springer.com/article/10.1007/s10470-024-02273-0","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"COMPUTER SCIENCE, HARDWARE & ARCHITECTURE","Score":null,"Total":0}
Active block EX-CCII based electrical circuit for practical impedance data of OSCC
Oral Squamous Cell Carcinoma (OSCC) is the most common oral cancer, and its behavior can be analyzed using bio-impedance. A single dispersion Cole model is designed using active block Extra X Current Conveyor (EX-CCII), which generates the existing practical oral OSCC bio-impedance data. An experimental result of cancer bio-impedance in the 20 Hz to 5 MHz range is well modeled with an active block EX-CCII resistors (R \(_{\infty }\) and R1) and fractional capacitor (Cα). The proposed design can serve as a step forward for designing a purposeful method for analyzing the behavior of oral cancer impedance without any practical data. The functionality of the proposed electrical circuit for OSCC is well verified through PSPICE simulation using both 0.25 μm CMOS TSMC Technology parameters and the macro model of EX-CCII. Simulation results agree well with experimental bio-impedance data.
期刊介绍：
Analog Integrated Circuits and Signal Processing is an archival peer reviewed journal dedicated to the design and application of analog, radio frequency (RF), and mixed signal integrated circuits (ICs) as well as signal processing circuits and systems. It features both new research results and tutorial views and reflects the large volume of cutting-edge research activity in the worldwide field today.
A partial list of topics includes analog and mixed signal interface circuits and systems; analog and RFIC design; data converters; active-RC, switched-capacitor, and continuous-time integrated filters; mixed analog/digital VLSI systems; wireless radio transceivers; clock and data recovery circuits; and high speed optoelectronic circuits and systems.
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