用纠缠光子对探测单层细胞培养物的偏振响应

IF 2 3区 物理与天体物理 Q3 BIOCHEMICAL RESEARCH METHODS
L. Zhang, V. R. Besaga, P. Rühl, C. Zou, S. H. Heinemann, Y. Wang, F. Setzpfandt
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引用次数: 0

摘要

本研究探讨了在低光子通量条件下生物样本鉴别光学检测方法对高信噪比的关键需求,以确保准确性,同时不影响样本的完整性。我们探索了基于偏振的探测方法,这种方法在评估标本形态时往往优于强度调制。借助非经典光源,我们的方法利用了亚泊松子光子统计和基于量子相关性的测量。我们提出了一种利用纠缠光子对探测单层细胞培养物的新型高灵敏度方法。我们的方法展示了单层细胞分析的潜力,可以区分两种类型的单层细胞及其宿主培养基。实验结果凸显了我们方法的灵敏度,展示了利用量子技术检测生物样本的潜力,并为先进的诊断方法铺平了道路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Probing polarization response of monolayer cell cultures with entangled photon pairs
This study addresses the critical need for high signal‐to‐noise ratio in optical detection methods for biological sample discrimination under low‐photon‐flux conditions to ensure accuracy without compromising sample integrity. We explore polarization‐based probing, which often excels over intensity modulation when assessing a specimen's morphology. Leveraging non‐classical light sources, our approach capitalizes on sub‐Poissonian photon statistics and quantum correlation‐based measurements. We present a novel, highly sensitive method for probing single‐layer cell cultures using entangled photon pairs. Our approach demonstrates potential for monolayer cell analysis, distinguishing between two types of monolayer cells and their host medium. The experimental results highlight our method's sensitivity, showcasing its potential for biological sample detection using quantum techniques, and paving the way for advanced diagnostic methodologies.
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来源期刊
Journal of Biophotonics
Journal of Biophotonics 生物-生化研究方法
CiteScore
5.70
自引率
7.10%
发文量
248
审稿时长
1 months
期刊介绍: The first international journal dedicated to publishing reviews and original articles from this exciting field, the Journal of Biophotonics covers the broad range of research on interactions between light and biological material. The journal offers a platform where the physicist communicates with the biologist and where the clinical practitioner learns about the latest tools for the diagnosis of diseases. As such, the journal is highly interdisciplinary, publishing cutting edge research in the fields of life sciences, medicine, physics, chemistry, and engineering. The coverage extends from fundamental research to specific developments, while also including the latest applications.
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