Sanjam Chandna, Kunal Gogde, Shatabdi Paul and Jayeeta Bhaumik
{"title":"用于生物医学设备消毒的木质素基可持续抗真菌凝胶纳米涂层","authors":"Sanjam Chandna, Kunal Gogde, Shatabdi Paul and Jayeeta Bhaumik","doi":"10.1039/D4SU00180J","DOIUrl":null,"url":null,"abstract":"<p >There is growing awareness that utilizing lignin as a sustainable biopolymer has emerged as a promising avenue to address challenges in antimicrobial protection. However, the application of lignin to prevent the spread of fungal infections is a less explored area and needs attention. Traditional antifungal agents often highlight significant concerns related to toxicity and environmental impact. To overcome these limitations, lignin, a renewable and biodegradable polyphenolic compound derived from plant cell walls, proves to be a substantial candidate. In this work, lignin is employed as a precursor molecule for the development of a gel-based coating. Rapid gelation technology was immensely useful in fabricating these versatile antifungal coatings. The developed coatings were highly transparent (nearly 85% transmittance values) and water resistant. Furthermore, the incorporation of lignin-based photodynamic nanoconjugates into coatings provides a multifaceted approach to combat fungal growth, thereby enhancing durability and sustainability, which enhanced the photodynamic activity of the lignin nanocoatings by approximately 50 fold. This work highlights the synergistic potential of lignin-based sustainable nanocoatings combined with photodynamic activity for on-demand disinfection of biomedical instruments.</p>","PeriodicalId":74745,"journal":{"name":"RSC sustainability","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/su/d4su00180j?page=search","citationCount":"0","resultStr":"{\"title\":\"Lignin-based sustainable antifungal gel nanocoatings for disinfecting biomedical devices†\",\"authors\":\"Sanjam Chandna, Kunal Gogde, Shatabdi Paul and Jayeeta Bhaumik\",\"doi\":\"10.1039/D4SU00180J\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >There is growing awareness that utilizing lignin as a sustainable biopolymer has emerged as a promising avenue to address challenges in antimicrobial protection. However, the application of lignin to prevent the spread of fungal infections is a less explored area and needs attention. Traditional antifungal agents often highlight significant concerns related to toxicity and environmental impact. To overcome these limitations, lignin, a renewable and biodegradable polyphenolic compound derived from plant cell walls, proves to be a substantial candidate. In this work, lignin is employed as a precursor molecule for the development of a gel-based coating. Rapid gelation technology was immensely useful in fabricating these versatile antifungal coatings. The developed coatings were highly transparent (nearly 85% transmittance values) and water resistant. Furthermore, the incorporation of lignin-based photodynamic nanoconjugates into coatings provides a multifaceted approach to combat fungal growth, thereby enhancing durability and sustainability, which enhanced the photodynamic activity of the lignin nanocoatings by approximately 50 fold. This work highlights the synergistic potential of lignin-based sustainable nanocoatings combined with photodynamic activity for on-demand disinfection of biomedical instruments.</p>\",\"PeriodicalId\":74745,\"journal\":{\"name\":\"RSC sustainability\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://pubs.rsc.org/en/content/articlepdf/2024/su/d4su00180j?page=search\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"RSC sustainability\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://pubs.rsc.org/en/content/articlelanding/2024/su/d4su00180j\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"RSC sustainability","FirstCategoryId":"1085","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2024/su/d4su00180j","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Lignin-based sustainable antifungal gel nanocoatings for disinfecting biomedical devices†
There is growing awareness that utilizing lignin as a sustainable biopolymer has emerged as a promising avenue to address challenges in antimicrobial protection. However, the application of lignin to prevent the spread of fungal infections is a less explored area and needs attention. Traditional antifungal agents often highlight significant concerns related to toxicity and environmental impact. To overcome these limitations, lignin, a renewable and biodegradable polyphenolic compound derived from plant cell walls, proves to be a substantial candidate. In this work, lignin is employed as a precursor molecule for the development of a gel-based coating. Rapid gelation technology was immensely useful in fabricating these versatile antifungal coatings. The developed coatings were highly transparent (nearly 85% transmittance values) and water resistant. Furthermore, the incorporation of lignin-based photodynamic nanoconjugates into coatings provides a multifaceted approach to combat fungal growth, thereby enhancing durability and sustainability, which enhanced the photodynamic activity of the lignin nanocoatings by approximately 50 fold. This work highlights the synergistic potential of lignin-based sustainable nanocoatings combined with photodynamic activity for on-demand disinfection of biomedical instruments.