{"title":"常压下 He + Ar + O2 等离子体射流的放电特性和活性物种诊断","authors":"Tongtong He, Yunzheng Wang, Zeyu Chen, Yuesheng Zheng","doi":"10.1140/epjd/s10053-024-00882-y","DOIUrl":null,"url":null,"abstract":"<div><p>Mixing helium and argon as the working gas of cold plasma jet is expected to combine the merits of He plasma jet and Ar plasma jet and has great potential for medical applications. For this reason, the discharge characteristics and reactive species diagnosis of a He + Ar + O<sub>2</sub> plasma jet were studied in this paper. The result shows that the Penning effect between He and Ar is strongest when the volume fraction of Ar in the working gas is 10%, and the plasma jet propagates the longest distance. A low drive voltage and a wide pulse width will weaken the Penning effect between He and Ar, resulting in a decrease in the ionization efficiency of the plasma jet. Gelatin gel was used as the model human tissue, and the effective treatment area of He + Ar + O<sub>2</sub> plasma jet on the model tissue increases with the volume fraction of Ar in the working gas. When the volume fraction of Ar is 50%, the effective treatment area of He + Ar + O<sub>2</sub> plasma jet is 9 times that of He + O<sub>2</sub> plasma jet, and the surface distribution of reactive oxygen species on the model tissue is almost uniform. Moreover, with the increase of volume fraction of Ar, the influence of the change of the plasma jet treatment angle on the surface distribution of reactive oxygen species is significantly weakened, indicating that He + Ar + O<sub>2</sub> plasma jet can precisely control the reactive species dosage on the living tissue for clinical application.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div><div><p>Surface distributions of ROS on the model tissue treated by the He + Ar + O<sub>2</sub> plasma jet under various argon volume fractions and treatment angles</p></div></div></figure></div></div>","PeriodicalId":789,"journal":{"name":"The European Physical Journal D","volume":"78 6","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Discharge characteristics and reactive species diagnosis of a He + Ar + O2 plasma jet at atmospheric pressure\",\"authors\":\"Tongtong He, Yunzheng Wang, Zeyu Chen, Yuesheng Zheng\",\"doi\":\"10.1140/epjd/s10053-024-00882-y\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Mixing helium and argon as the working gas of cold plasma jet is expected to combine the merits of He plasma jet and Ar plasma jet and has great potential for medical applications. For this reason, the discharge characteristics and reactive species diagnosis of a He + Ar + O<sub>2</sub> plasma jet were studied in this paper. The result shows that the Penning effect between He and Ar is strongest when the volume fraction of Ar in the working gas is 10%, and the plasma jet propagates the longest distance. A low drive voltage and a wide pulse width will weaken the Penning effect between He and Ar, resulting in a decrease in the ionization efficiency of the plasma jet. Gelatin gel was used as the model human tissue, and the effective treatment area of He + Ar + O<sub>2</sub> plasma jet on the model tissue increases with the volume fraction of Ar in the working gas. When the volume fraction of Ar is 50%, the effective treatment area of He + Ar + O<sub>2</sub> plasma jet is 9 times that of He + O<sub>2</sub> plasma jet, and the surface distribution of reactive oxygen species on the model tissue is almost uniform. Moreover, with the increase of volume fraction of Ar, the influence of the change of the plasma jet treatment angle on the surface distribution of reactive oxygen species is significantly weakened, indicating that He + Ar + O<sub>2</sub> plasma jet can precisely control the reactive species dosage on the living tissue for clinical application.</p><h3>Graphical Abstract</h3>\\n<div><figure><div><div><picture><source><img></source></picture></div><div><p>Surface distributions of ROS on the model tissue treated by the He + Ar + O<sub>2</sub> plasma jet under various argon volume fractions and treatment angles</p></div></div></figure></div></div>\",\"PeriodicalId\":789,\"journal\":{\"name\":\"The European Physical Journal D\",\"volume\":\"78 6\",\"pages\":\"\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2024-06-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The European Physical Journal D\",\"FirstCategoryId\":\"4\",\"ListUrlMain\":\"https://link.springer.com/article/10.1140/epjd/s10053-024-00882-y\",\"RegionNum\":4,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"OPTICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The European Physical Journal D","FirstCategoryId":"4","ListUrlMain":"https://link.springer.com/article/10.1140/epjd/s10053-024-00882-y","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPTICS","Score":null,"Total":0}
引用次数: 0
摘要
将氦气和氩气混合作为冷等离子体射流的工作气体，有望结合氦等离子体射流和氩等离子体射流的优点，在医疗应用方面具有巨大潜力。为此，本文研究了 He + Ar + O2 等离子体射流的放电特性和反应物诊断。结果表明，当工作气体中 Ar 的体积分数为 10%时，He 和 Ar 之间的潘宁效应最强，等离子体射流的传播距离最长。低驱动电压和宽脉冲宽度会减弱 He 和 Ar 之间的潘宁效应，导致等离子体射流的电离效率降低。以明胶作为人体组织模型，He + Ar + O2 等离子体射流对模型组织的有效治疗面积随工作气体中 Ar 体积分数的增加而增大。当 Ar 的体积分数为 50%时，He + Ar + O2 等离子体射流的有效治疗面积是 He + O2 等离子体射流的 9 倍，模型组织上活性氧的表面分布基本均匀。此外，随着 Ar 体积分数的增加，等离子体射流处理角度的变化对活性氧表面分布的影响明显减弱，这表明 He + Ar + O2 等离子体射流可以精确控制活性氧在活体组织上的用量，适合临床应用。
Discharge characteristics and reactive species diagnosis of a He + Ar + O2 plasma jet at atmospheric pressure
Mixing helium and argon as the working gas of cold plasma jet is expected to combine the merits of He plasma jet and Ar plasma jet and has great potential for medical applications. For this reason, the discharge characteristics and reactive species diagnosis of a He + Ar + O2 plasma jet were studied in this paper. The result shows that the Penning effect between He and Ar is strongest when the volume fraction of Ar in the working gas is 10%, and the plasma jet propagates the longest distance. A low drive voltage and a wide pulse width will weaken the Penning effect between He and Ar, resulting in a decrease in the ionization efficiency of the plasma jet. Gelatin gel was used as the model human tissue, and the effective treatment area of He + Ar + O2 plasma jet on the model tissue increases with the volume fraction of Ar in the working gas. When the volume fraction of Ar is 50%, the effective treatment area of He + Ar + O2 plasma jet is 9 times that of He + O2 plasma jet, and the surface distribution of reactive oxygen species on the model tissue is almost uniform. Moreover, with the increase of volume fraction of Ar, the influence of the change of the plasma jet treatment angle on the surface distribution of reactive oxygen species is significantly weakened, indicating that He + Ar + O2 plasma jet can precisely control the reactive species dosage on the living tissue for clinical application.
Graphical Abstract
Surface distributions of ROS on the model tissue treated by the He + Ar + O2 plasma jet under various argon volume fractions and treatment angles
期刊介绍：
The European Physical Journal D (EPJ D) presents new and original research results in:
Atomic Physics;
Molecular Physics and Chemical Physics;
Atomic and Molecular Collisions;
Clusters and Nanostructures;
Plasma Physics;
Laser Cooling and Quantum Gas;
Nonlinear Dynamics;
Optical Physics;
Quantum Optics and Quantum Information;
Ultraintense and Ultrashort Laser Fields.
The range of topics covered in these areas is extensive, from Molecular Interaction and Reactivity to Spectroscopy and Thermodynamics of Clusters, from Atomic Optics to Bose-Einstein Condensation to Femtochemistry.
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