过敏性支气管肺曲霉菌病,同时分离出三种不同的曲霉菌。

IF 0.8 Q4 RESPIRATORY SYSTEM
Respirology Case Reports Pub Date : 2024-07-03 eCollection Date: 2024-07-01 DOI:10.1002/rcr2.1423
Yosuke Sasahara, Kentaro Akata, Kei Yamasaki, Takeshi Orihashi, Kazuhiro Yatera
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引用次数: 0

摘要

过敏性支气管肺曲霉菌病(ABPA)是一种由曲霉菌引起的夸张免疫反应诱发的炎症性疾病。虽然 ABPA 的复发率很高(48%),但其连续分离出不同曲霉菌种的病例却很少见。只有一份病例报告记录了烟曲霉和黄曲霉的同时分离。然而,目前还没有涉及三个不同曲霉菌种的同时分离病例的报道。在此,我们报告了一例新病例,患者是一名 47 岁的日本男子,他先后分离出了黄曲霉、赤曲霉和烟曲霉。患者最初表现为有痰咳嗽和肺部浸润症状,口服泼尼松龙治疗后两次复发。通过调整治疗方案,包括伏立康唑和量身定制的皮质类固醇治疗方案,患者的病情得到了明显改善,并在超过 6 个月的时间里没有复发。本病例报告强调了涉及多种曲霉菌的 ABPA 的挑战和成功治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Allergic bronchopulmonary aspergillosis with metachronous isolation of three distinct Aspergillus species.

Allergic bronchopulmonary aspergillosis (ABPA) is an inflammatory disease induced by exaggerated immune responses to Aspergillus species. Although ABPA has a high recurrence (48%), its instances with sequential isolation of distinct Aspergillus species are sporadic. Only one case report has documented the metachronous isolation of Aspergillus fumigatus and Aspergillus flavus. However, no reported cases of metachronous isolation involving three distinct Aspergillus species exist. Herein, we report a novel case of a 47-year-old Japanese man with sequential metachronous isolation of A. flavus, A. terreus, and A. fumigatus. Initially presenting with symptoms of productive cough and pulmonary infiltration, the patient experienced two relapses following treatment with oral prednisolone. Adjustments in therapy, including voriconazole and a tailored corticosteroid regimen, resulted in significant improvement without relapse for over 6 months. This case report highlights the challenges and successful management of ABPA involving multiple Aspergillus species.

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来源期刊
Respirology Case Reports
Respirology Case Reports RESPIRATORY SYSTEM-
CiteScore
1.40
自引率
0.00%
发文量
178
审稿时长
8 weeks
期刊介绍: Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.
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