空气污染与血压:印度尼西亚的证据。

IF 4.3 2区 医学 Q2 ENVIRONMENTAL SCIENCES
Geohealth Pub Date : 2024-07-02 DOI:10.1029/2024GH001014
Jaime Madrigano, Daisy Yan, Tianjia Liu, Eimy Bonilla, Nina Yulianti, Loretta J. Mickley, Miriam E. Marlier
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引用次数: 0

摘要

由于多种排放源,包括快速城市化和与农业土地管理相关的泥炭地火灾,印度尼西亚面临着严重的空气质量问题。以前的研究对印尼强烈火灾对发病率和死亡率造成的偶发性冲击进行了有限的估计,但在很大程度上忽略了全年空气质量差对心血管疾病风险生物标志物的影响。我们对直径小于 2.5 微米的颗粒物(PM2.5)与血压之间的关系进行了横断面研究。血压测量数据来自第五次印度尼西亚家庭生活调查(IFLS5),这是一项基于人口的社会经济和健康调查。我们使用 GEOS-Chem 化学传输模型,以 0.5° × 0.625° 的分辨率模拟了 IFLS 域内 PM2.5 的日浓度。我们使用混合效应模型评估了 PM2.5 与舒张压和收缩压之间的关系,该模型对地区/城市和家庭进行了随机截距,并对个体协变量进行了调整。PM2.5月暴露量的四分位数间距增加与舒张压升高0.234(95% CI:0.003,0.464)有关,65岁及以上参与者的相关性更大(1.16 [95% CI:0.24,2.08])。对于相同的暴露指标,65 岁及以上的参与者收缩压升高 1.90(95% CI:0.43,3.37)。我们对火灾特异性 PM2.5 的评估结果为空,这可能与健康数据收集的时间和地点有关。据我们所知,这是第一项为印度尼西亚 PM2.5 与血压之间的关系提供证据的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Air Pollution and Blood Pressure: Evidence From Indonesia

Air Pollution and Blood Pressure: Evidence From Indonesia

Indonesia faces significant air quality issues due to multiple emissions sources, including rapid urbanization and peatland fires associated with agricultural land management. Limited prior research has estimated the episodic shock of intense fires on morbidity and mortality in Indonesia but has largely ignored the impact of poor air quality throughout the year on biomarkers of cardiovascular disease risk. We conducted a cross-sectional study of the association between particulate matter less than 2.5 microns in diameter (PM2.5) and blood pressure. Blood pressure measurements were obtained from the fifth wave of the Indonesian Family Life Survey (IFLS5), an ongoing population-based socioeconomic and health survey. We used the GEOS-Chem chemical transport model to simulate daily PM2.5 concentrations at 0.5° × 0.625° resolution across the IFLS domain. We assessed the association between PM2.5 and diastolic and systolic blood pressure, using mixed effects models with random intercepts for regency/municipality and household and adjusted for individual covariates. An interquartile range increase in monthly PM2.5 exposure was associated with a 0.234 (95% CI: 0.003, 0.464) higher diastolic blood pressure, with a greater association seen in participants age 65 and over (1.16 [95% CI: 0.24, 2.08]). For the same exposure metric, there was a 1.90 (95% CI: 0.43, 3.37) higher systolic blood pressure in participants 65 and older. Our assessment of fire-specific PM2.5 yielded null results, potentially due to the timing and locations of health data collection. To our knowledge, this is the first study to provide evidence for an association between PM2.5 and blood pressure in Indonesia.

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来源期刊
Geohealth
Geohealth Environmental Science-Pollution
CiteScore
6.80
自引率
6.20%
发文量
124
审稿时长
19 weeks
期刊介绍: GeoHealth will publish original research, reviews, policy discussions, and commentaries that cover the growing science on the interface among the Earth, atmospheric, oceans and environmental sciences, ecology, and the agricultural and health sciences. The journal will cover a wide variety of global and local issues including the impacts of climate change on human, agricultural, and ecosystem health, air and water pollution, environmental persistence of herbicides and pesticides, radiation and health, geomedicine, and the health effects of disasters. Many of these topics and others are of critical importance in the developing world and all require bringing together leading research across multiple disciplines.
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