暴露前预防时代假定的艾滋病疫苗的可接受性、促进因素和障碍。

IF 1.2 4区 医学 Q4 HEALTH POLICY & SERVICES
Aaron Richterman, Caroline O'Brien, Fatemeh Ghadimi, Elijah Sumners, Andre Ford, Nafisah Houston, Sebrina Tate, Nancy Aitcheson, Hervette Nkwihoreze, John B Jemmott, Florence Momplaisir
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引用次数: 0

摘要

人们对预防性艾滋病疫苗实施前的情况知之甚少。我们对费城宾大诊所和社区组织招募的人员进行了访谈,这些人员的服务对象是具有 LGBTQ 特征的有色人种,他们 1) 是与男性发生过性关系的顺性别男性,或具有跨性别特征;2) 在过去 12 个月内曾感染过性传播疾病,或在过去两周内与多个性伴侣发生过性关系。我们采用综合分析方法评估了假定的 HIV 疫苗的可接受性、促进因素和障碍。我们在 2023 年 2 月至 2023 年 9 月期间对 30 人进行了访谈。参与者对 HIV 疫苗持支持态度,并表示如果有疫苗,他们会积极考虑接种。参与者将假想疫苗与当前的艾滋病预防环境(主要是暴露前预防(PrEP))结合起来,表示他们会将未来的疫苗与他们在 PrEP 环境中的经验进行比较评估。阻碍因素包括:对疫苗的目的缺乏了解;对寻求接种疫苗的人可能会产生的有关艾滋病毒和性行为的污名化;有效性、副作用或缺乏可用性方面的潜在问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acceptability, facilitators, and barriers to a hypothetical HIV vaccine in the pre-exposure prophylaxis era.

Little is known about the pre-implementation context for a preventive HIV vaccine. We conducted interviews of individuals in Philadelphia recruited at Penn clinics and community-based organizations serving LGBTQ-identifying persons of color who 1) were cisgender men who had sex with men, or were transgender-identified, 2) had a sexually transmitted infection in the last 12 months, or sex with multiple partners within the last two weeks. We assessed acceptability, facilitators, and barriers to a hypothetical HIV vaccine using an integrated analysis approach. We interviewed 30 individuals between 2/2023-9/2023. Participants were supportive of an HIV vaccine and reported that they would strongly consider receiving one if one became available. Participants contextualized a hypothetical vaccine with the current HIV prevention context, primarily pre-exposure prophylaxis (PrEP), indicating that they would evaluate any future vaccine in comparison to their experience within the PrEP landscape.Reported facilitators for a hypothetical HIV vaccine included vaccine access, knowledge, and understanding; their risk for HIV exposure; and perceived benefits of the vaccine. Barriers included lack of understanding of the purpose of a vaccine, stigma surrounding HIV and sexual practices that may surface towards people who seek vaccination, and potential issues with effectiveness, side effects, or lack of availability.

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CiteScore
3.50
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