哭泣、扫地和扫帚：丛细胞乙酰胆碱限制了蠕虫。

IF 7 1区医学 Q1 PARASITOLOGY

Trends in parasitology Pub Date : 2024-08-01 Epub Date: 2024-07-01 DOI:10.1016/j.pt.2024.06.014

Alexander Perniss, Lora G Bankova

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引用次数: 0

摘要

两项研究确定了丛细胞乙酰胆碱如何促进寄生虫的排出。Billip 等人证实，乙酰胆碱能增加水分分泌，促进 "哭泣 "反应。Ndjim 等人发现，丛细胞乙酰胆碱对蠕虫的繁殖力有直接影响。只有当稀有的簇细胞变得丰富时，这两个过程才会在重塑的上皮细胞中发挥作用。

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Weep and sweep and the broom: tuft cell acetylcholine limits the worm.

Two studies defined how tuft cell acetylcholine promotes parasite expulsion. Billip et al. demonstrated that acetylcholine increases water secretion, to promote the 'weep' response. Ndjim et al. found that tuft cell acetylcholine has a direct effect on worm fecundity. Both processes are only effective in the remodeled epithelium when the rare tuft cells have become abundant.

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来源期刊

Trends in parasitology 医学-寄生虫学

CiteScore

14.00

自引率

3.10%

发文量

148

审稿时长

6-12 weeks

期刊介绍： Since its inception as Parasitology Today in 1985, Trends in Parasitology has evolved into a highly esteemed review journal of global significance, reflecting the importance of medical and veterinary parasites worldwide. The journal serves as a hub for communication among researchers across all disciplines of parasitology, encompassing endoparasites, ectoparasites, transmission vectors, and susceptible hosts. Each monthly issue of Trends in Parasitology offers authoritative, cutting-edge, and yet accessible review articles, providing a balanced and comprehensive overview, along with opinion pieces offering personal and novel perspectives. Additionally, the journal publishes a variety of short articles designed to inform and stimulate thoughts in a lively and widely-accessible manner. These include Science & Society (discussing the interface between parasitology and the general public), Spotlight (highlighting recently published research articles), Forum (presenting single-point hypotheses), Parasite/Vector of the Month (featuring a modular display of the selected species), Letter (providing responses to recent articles in Trends in Parasitology), and Trendstalk (conducting interviews). Please note that the journal exclusively publishes literature reviews based on published data, with systematic reviews, meta-analysis, and unpublished primary research falling outside our scope.