适合目的：选择最合适的线粒体 DNA

IF 27.7 1区生物学 Q1 CELL BIOLOGY

Cell metabolism Pub Date : 2024-07-02 DOI:10.1016/j.cmet.2024.06.011

Sarah J. Pickett, Robert W. Taylor, Robert McFarland

引用次数: 0

摘要

决定细胞和组织中致病线粒体 DNA 水平的因素对疾病病理至关重要，但人们对这些因素的了解仍然很少，而且存在争议。在《自然》杂志上，Kotrys 等人发表了一项基于单细胞的分析，为这一棘手问题带来了新的曙光，并引入了一种强大的新研究工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Fit for purpose: Selecting the best mitochondrial DNA for the job

The factors determining levels of pathogenic mitochondrial DNA in cells and tissues are critical to disease pathology but remain poorly understood and contentious. In Nature, Kotrys et al. published a single-cell-based analysis casting fresh light on this thorny problem and introduced a powerful new investigative tool.

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来源期刊

Cell metabolism 生物-内分泌学与代谢

CiteScore

48.60

自引率

1.40%

发文量

173

审稿时长

2.5 months

期刊介绍： Cell Metabolism is a top research journal established in 2005 that focuses on publishing original and impactful papers in the field of metabolic research.It covers a wide range of topics including diabetes, obesity, cardiovascular biology, aging and stress responses, circadian biology, and many others. Cell Metabolism aims to contribute to the advancement of metabolic research by providing a platform for the publication and dissemination of high-quality research and thought-provoking articles.