{"title":"有关氯氮平诱发粒细胞减少症的数据表明，可以放松监测","authors":"","doi":"10.1002/pu.31186","DOIUrl":null,"url":null,"abstract":"<p>A nationwide cohort study conducted in Finland has found that risk of clozapine-induced agranulocytosis, while greater than that associated with other antipsychotics, decreases considerably with longer-term use of the medication. The study's findings lend support to the idea that hematological monitoring requirements for patients receiving clozapine could be relaxed over time, the investigators stated. Study results were published online April 29, 2024, in <i>Lancet Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Data on clozapine-induced agranulocytosis suggest monitoring could be relaxed\",\"authors\":\"\",\"doi\":\"10.1002/pu.31186\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A nationwide cohort study conducted in Finland has found that risk of clozapine-induced agranulocytosis, while greater than that associated with other antipsychotics, decreases considerably with longer-term use of the medication. The study's findings lend support to the idea that hematological monitoring requirements for patients receiving clozapine could be relaxed over time, the investigators stated. Study results were published online April 29, 2024, in <i>Lancet Psychiatry</i>.</p>\",\"PeriodicalId\":22275,\"journal\":{\"name\":\"The Brown University Psychopharmacology Update\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Brown University Psychopharmacology Update\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/pu.31186\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31186","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Data on clozapine-induced agranulocytosis suggest monitoring could be relaxed
A nationwide cohort study conducted in Finland has found that risk of clozapine-induced agranulocytosis, while greater than that associated with other antipsychotics, decreases considerably with longer-term use of the medication. The study's findings lend support to the idea that hematological monitoring requirements for patients receiving clozapine could be relaxed over time, the investigators stated. Study results were published online April 29, 2024, in Lancet Psychiatry.
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