Leyla Namazova-Baranova , Kamilla Efendieva , Julia Levina , Vera Kalugina
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引用次数: 0
摘要
准确识别患者对食物的反应是食物过敏(FA)还是食物不耐受(FI)所致至关重要,因为这将决定适当的诊断和治疗方案。医疗从业人员在讨论这些病症的患病率时,应以经过核实的诊断结果为依据。目前,获取患者的临床病史、进行皮肤点刺试验 (SPT) 或测量血清特异性 IgE 水平通常是诊断过敏症的初始步骤。如果有其他方法,如成分解析诊断法、嗜碱性粒细胞活化试验(BAT)和口服食物挑战(OFC),可用于在一线检测结果不明确或与病史相矛盾时确认引起症状的过敏原。考虑到地域特点,确定不同过敏原的致敏特征对于制定针对儿童的个性化治疗和预防措施非常重要。通过过敏测试和口服食物挑战对 FA 患者进行定期重新评估,可以在患者逐渐产生耐受性的情况下重新引入之前避免食用的食物,从而改善他们的生活质量。
Food Allergy and Food Intolerance – New Developments
It is crucial to accurately identify whether a patient's reaction to food is a result of a Food Allergy (FA) or Food Intolerance (FI), as this will determine the appropriate diagnosis and management plan. Medical practitioners should rely on verified diagnoses when discussing the prevalence of these conditions. Currently, obtaining a patient's clinical history, performing a skin prick test (SPT) or measuring serum specific IgE levels are typically the initial steps in diagnosing allergies. Additional methods, such as component-resolved diagnostics, basophil activation test (BAT) and oral food challenge (OFC) may be used, if available, to confirm the allergen causing symptoms when the results of first-line tests are equivocal or contradictory with history. Determining the prevalence of sensitization profiles to different allergens, considering geographical characteristics, is important for developing personalized therapeutic and preventive measures for children. Periodic reassessment of patients with FA through allergy tests and oral food challenges will allow for the possibility of reintroducing previously avoided foods if they develop tolerance over time and improve their quality of life.