耐万古霉素肠球菌：全球健康面临的日益严峻的挑战

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2024-07-01 DOI:10.1016/j.cegh.2024.101663

Faiza Iqbal , Arya Alocious , Selin C. Joy , Elstin Anbu Raj Stanly , V. Rajesh , M.K. Unnikrishnan , Douglas Steinke , Prashant Chandra

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引用次数: 0

摘要

导言抗生素使用不当会引发医院获得性 VRE 感染的爆发。相关研究来自 Scopus 和 PubMed。二十年来，疱疹病毒在全球人类和动物中的流行率从 0.05% 增长到 99.0%，在印度从 1.0% 增长到 45.6%。结果和结论VRE感染，尤其是血流感染，造成了严重的死亡率（全球60-70%；印度23%）和经济负担（5.39亿美元）。利奈唑胺和达托霉素在没有充分临床试验证据的情况下被频繁使用。印度缺乏对流行率、死亡率和成本的研究，这需要政治意愿、公私合作以及优先考虑公共卫生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Vancomycin-resistant enterococci: A rising challenge to global health

Introduction

Improper antibiotic use triggers outbreaks of hospital-acquired VRE infections. Relevant studies were gathered from Scopus, and PubMed. Over two decades, prevalence of VRE in humans and animals grew from 0.05 % to 99.0 % globally and from 1.0 % to 45.6 % in India. Identifying VRE at the species level helps identify acquired/intrinsic resistance.

Results and conclusion

VRE infections, especially bloodstream infections, inflict significant mortality (60-70%-global; 23%-India) and economic burden ($539 million). Linezolid and daptomycin are frequently used without adequate clinical trial evidence. India lacks studies on prevalence, mortality and cost, which needs political will, public-private partnership, and prioritizing public health.

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.