波兰 2013-2019 年实施肿瘤治疗套餐对直肠癌治疗的影响 - 多中心研究。

Jerzy Krzeszowiak, Radosław Pach, Piotr Richter, Zbigniew Lorenc, Andrzej Rutkowski, Kajetan Ochwat, Wojciech Zegarski, Mariusz Frączek, Antoni Szczepanik
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引用次数: 0

摘要

<b><br>引言:</b>2015年,波兰制定了肿瘤一揽子计划(OP)。该法律规定了肿瘤诊断和治疗的快速通道,以及多学科团队会议(MDT)的义务。</br><b></br>方法:</b>本研究是一项多中心、回顾性分析,数据来自五个中心。其中包括 2013 年至 2019 年期间因直肠癌接受手术的患者的临床数据。在大多数分析中,患者被分为三组:2013-2014 年--OP 前(A 组),2015-2016 年--OP 早期发展(B 组),2017-2019 年--OP 进一步发挥作用(C 组)。在所有时间间隔内,大部分手术都是前路切除。在随后的时间段中,观察到局部肿瘤分期(T)明显降低,而N和M没有明显差异。其中四个中心的术前放疗使用率呈上升趋势。研究表明,短程放疗(SCRT)的使用率明显增加,而在随后几个时期未接受任何形式术前治疗的患者人数有所减少。在应该接受放疗的人群(T3/4 或 N+ 和 M0)中,SCRT 的使用率也明显增加。不过,这种关系是间接的,应收集更多数据才能得出进一步结论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The impact of oncological package implementation on the treatment of rectal cancer in years 2013-2019 in Poland - multicenter study.

<b><br>Introduction:</b> In 2015, in Poland, the oncological package (OP) was established. This law constituted a fast track of oncological diagnosis and treatment and obligatory multidisciplinary team meetings (MDT).</br> <b><br>Aim:</b> The aim of this study was to analyze the impact of OP on rectal cancer treatment.</br> <b><br>Methods:</b> The study was a multicenter, retrospective analysis of data collected from five centers. It included clinical data of patients operated on due to rectal cancer between 2013 and 2019. For most analyses, patients were categorized into three groups: 2013-2014 - before OP (A), 2015-2016 - early development of OP (B), 2017-2019 - further OP functioning (C).</br> <b><br>Results:</b> A total of 1418 patients were included. In all time intervals, the majority of operations performed were anterior resections. There was a significantly lower local tumor stage (T) observed in subsequent time intervals, while there were no significant differences for N and M. In period C, the median of resected nodes was significantly higher than in previous periods. Four of the centers showed an increasing tendency in the use of preoperative radiotherapy. The study indicated a significant increase in the use of short-course radiotherapy (SCRT) and a decrease in the number of patients who did not receive any form of preoperative therapy in subsequent periods. In the group that should receive radiotherapy (T3/4 or N+ and M0), the use of SCRT was also significantly increasing.</br> <b><br>Conclusions:</b> In the whole cohort, there was a significant increase in the use of preoperative radiotherapy and a decrease in the T stage, changing with the development of OP. Nevertheless, this relation is indirect and more data should be gathered for further conclusions.</br>.

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