Chiachi Bonnie Lee , Li-Jung Elizabeth Ku , Yu-Tsung Chou , Hung-Yu Chen , Hui-Chen Su , Yi-Lin Wu , Yu-Tai Lo , Yi-Ching Yang , Chung-Yi Li
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The Integrated Care for Older People Screening Tool for Taiwanese and the Adherence to Refills and Medication Scale were used to assess IC and medication non-adherence, respectively. Latent class analysis (LCA) was used to identify patterns of IC impairment, and binary logistic regression was used to assess the association between medication non-adherence and IC.</p></div><div><h3>Results</h3><p>Older adults in the moderate (score: 1–2) or low (score≧3) overall IC groups were more likely to experience medication non-adherence (moderate: adjusted odds ratio (aOR) 1.57 [95% CI: 1.05–2.36]; low: 2.26 [1.40–3.67]). The “physical and nutritional impairments accompanied by depressive symptoms” group was associated with statistically higher odds of medication non-adherence (aOR 1.66 [1.01–2.73]). Older adults with cognitive impairment, hearing loss, or depressive symptoms showed greater likelihood of medication non-adherence (cognitive impairment: aOR 1.53 [1.03–2.27]; hearing loss: aOR 1.57 [1.03–2.37]; depressive symptoms: aOR 1.81 [1.17–2.80]).</p></div><div><h3>Conclusions</h3><p>Intervention for improving medication non-adherence among older adults with NCDs should consider IC.</p></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724003907/pdfft?md5=1a097aa09d7e5eef9e58a6c66a3ef4bb&pid=1-s2.0-S1279770724003907-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Association of intrinsic capacity and medication non-adherence among older adults with non-communicable diseases in Taiwan\",\"authors\":\"Chiachi Bonnie Lee , Li-Jung Elizabeth Ku , Yu-Tsung Chou , Hung-Yu Chen , Hui-Chen Su , Yi-Lin Wu , Yu-Tai Lo , Yi-Ching Yang , Chung-Yi Li\",\"doi\":\"10.1016/j.jnha.2024.100303\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><p>Medication non-adherence among older adults with non-communicable diseases (NCDs) remains prevalent worldwide, which causes hospitalization and mortality. 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引用次数: 0
摘要
目的：患有非传染性疾病（NCDs）的老年人不遵医嘱用药的现象在全球仍很普遍，这导致了住院和死亡。我们的研究旨在探讨非传染性疾病老年人不遵医嘱用药与总体内在能力（IC）水平、内在能力模式和特定内在能力组成部分之间的关系：方法：2022 年在台湾南部对 1268 名 60 岁及以上的老年人进行了横断面问卷调查。方法：2022 年在台湾南部对 1268 名 60 岁以上的老年人进行了横断面问卷调查，其中 894 名老年人患有 1 种以上的非传染性疾病。研究使用台湾老年人综合护理筛查工具（Integrated Care for Older People Screening Tool for Taiwanese）和 "续药和用药依从性量表"（Adherence to Refills and Medication Scale）分别对IC和用药不依从性进行评估。研究采用潜类分析法（LCA）确定IC受损的模式，并采用二元逻辑回归法评估不遵医嘱用药与IC之间的关联：中度（得分：1-2）或低度（得分≧3）总体 IC 组的老年人更有可能出现不坚持用药的情况（中度：调整后的几率比（aOR）为 1.57 [95% CI：1.05-2.36]；低度：2.26 [1.40-3.67]）。在统计学上，"身体和营养受损并伴有抑郁症状 "组出现不遵医嘱用药的几率更高（aOR：1.66 [1.01-2.73]）。有认知障碍、听力损失或抑郁症状的老年人不坚持服药的可能性更大（认知障碍：aOR 1.53 [1.03-2.27]；听力损失：aOR 1.57 [1.03-2.37]；抑郁症状：aOR 1.81 [1.17-2.80]）：结论：改善患有非传染性疾病的老年人不遵医嘱用药的干预措施应考虑 IC。
Association of intrinsic capacity and medication non-adherence among older adults with non-communicable diseases in Taiwan
Objectives
Medication non-adherence among older adults with non-communicable diseases (NCDs) remains prevalent worldwide, which causes hospitalization and mortality. Our study aimed to examine the association of medication non-adherence with level of overall intrinsic capacity (IC), pattern of IC, and specific IC component among older adults with NCDs.
Methods
A cross-sectional questionnaire-based survey of 1268 older adults aged 60 years and above was conducted in 2022 in southern Taiwan. Among them, 894 suffered from 1 more NCD were included in this study. The Integrated Care for Older People Screening Tool for Taiwanese and the Adherence to Refills and Medication Scale were used to assess IC and medication non-adherence, respectively. Latent class analysis (LCA) was used to identify patterns of IC impairment, and binary logistic regression was used to assess the association between medication non-adherence and IC.
Results
Older adults in the moderate (score: 1–2) or low (score≧3) overall IC groups were more likely to experience medication non-adherence (moderate: adjusted odds ratio (aOR) 1.57 [95% CI: 1.05–2.36]; low: 2.26 [1.40–3.67]). The “physical and nutritional impairments accompanied by depressive symptoms” group was associated with statistically higher odds of medication non-adherence (aOR 1.66 [1.01–2.73]). Older adults with cognitive impairment, hearing loss, or depressive symptoms showed greater likelihood of medication non-adherence (cognitive impairment: aOR 1.53 [1.03–2.27]; hearing loss: aOR 1.57 [1.03–2.37]; depressive symptoms: aOR 1.81 [1.17–2.80]).
Conclusions
Intervention for improving medication non-adherence among older adults with NCDs should consider IC.
期刊介绍：
There is increasing scientific and clinical interest in the interactions of nutrition and health as part of the aging process. This interest is due to the important role that nutrition plays throughout the life span. This role affects the growth and development of the body during childhood, affects the risk of acute and chronic diseases, the maintenance of physiological processes and the biological process of aging. A major aim of "The Journal of Nutrition, Health & Aging" is to contribute to the improvement of knowledge regarding the relationships between nutrition and the aging process from birth to old age.
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