慢性伤口的种族/族裔差异:将上游因素与健康结果联系起来的视角。

IF 3.8 3区 医学 Q2 CELL BIOLOGY
Wound Repair and Regeneration Pub Date : 2024-09-01 Epub Date: 2024-06-29 DOI:10.1111/wrr.13200
Jacqueline Cavalcante-Silva, Giamila Fantuzzi, Richard Minshall, Stephanie Wu, Vanessa M Oddo, Timothy J Koh
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引用次数: 0

摘要

这篇综述探讨了健康的社会决定因素与糖尿病相关慢性伤口生物学之间的复杂关系,重点是种族/民族差异。慢性伤口给医疗保健带来了巨大挑战,常常导致美国数百万人出现严重并发症,对非洲裔美国人、西班牙裔美国人和美国原住民的影响尤为严重。健康的社会决定因素包括经济稳定性、获得医疗保健的机会、教育和环境条件,这些因素可能会影响压力、风化和营养,从而共同形成对肥胖和糖尿病等慢性疾病的易感性,以及慢性伤口和随后的下肢截肢风险的升高。在此,我们回顾了这些问题,并讨论了进一步研究的迫切需要,研究重点是了解慢性伤口的种族/民族差异背后的机制,特别是社会剥夺、风化和营养,以便为解决这些差异的干预措施提供信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Racial/ethnic disparities in chronic wounds: Perspectives on linking upstream factors to health outcomes.

This review explores the complex relationship between social determinants of health and the biology of chronic wounds associated with diabetes mellitus, with an emphasis on racial/ethnic disparities. Chronic wounds pose significant healthcare challenges, often leading to severe complications for millions of people in the United States, and disproportionally affect African American, Hispanic, and Native American individuals. Social determinants of health, including economic stability, access to healthcare, education, and environmental conditions, likely influence stress, weathering, and nutrition, collectively shaping vulnerability to chronic diseases, such as obesity and DM, and an elevated risk of chronic wounds and subsequent lower extremity amputations. Here, we review these issues and discuss the urgent need for further research focusing on understanding the mechanisms underlying racial/ethnic disparities in chronic wounds, particularly social deprivation, weathering, and nutrition, to inform interventions to address these disparities.

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来源期刊
Wound Repair and Regeneration
Wound Repair and Regeneration 医学-皮肤病学
CiteScore
5.90
自引率
3.40%
发文量
71
审稿时长
6-12 weeks
期刊介绍: Wound Repair and Regeneration provides extensive international coverage of cellular and molecular biology, connective tissue, and biological mediator studies in the field of tissue repair and regeneration and serves a diverse audience of surgeons, plastic surgeons, dermatologists, biochemists, cell biologists, and others. Wound Repair and Regeneration is the official journal of The Wound Healing Society, The European Tissue Repair Society, The Japanese Society for Wound Healing, and The Australian Wound Management Association.
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