日粮姜黄素纳米微粒对不同温湿度指数条件下热应激育肥羔羊的性能、生物反应和热应激复原力的影响:对气候变化的影响。

IF 2.9 2区 生物学 Q2 BIOLOGY
Mostafa Bokharaeian, Abdolhakim Toghdory, Taghi Ghoorchi
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引用次数: 0

摘要

热应激对干旱和半干旱地区的绵羊养殖构成了巨大挑战,会影响绵羊的生长性能、健康和生理反应。虽然绵羊具有控制热应激的先天机制,但长时间暴露在热应激下会损害其生长性能和健康。本研究评估了不同剂量的姜黄素纳米微粒(CNM)在三个月内对伊朗东北部热应激育肥羔羊的影响,考察了 CNM 剂量与生长性能、采食行为、生理反应、免疫功能和抗氧化状态之间的关系。32 只杂交雄性羔羊采用完全随机设计,共设四个处理和八个重复。实验处理如下1) CTRL:不在膳食中添加氯化萘(对照组);2)T20:每天每头羔羊膳食中添加 20 毫克氯化萘;3)T40:每天每头羔羊膳食中添加 40 毫克氯化萘;4)T80:每天每头羔羊膳食中添加 80 毫克氯化萘:4) T80:每人每天摄入 80 毫克氯化萘。结果表明,与对照组相比,日粮添加 20 毫克和 40 毫克 CNM 可显著提高活体重、增重、平均日增重 (ADG) 和饲料转化率 (FCR)。回归分析表明,生长性能参数与温湿度指数(THI)之间存在二次模型,表明 CNM 剂量与动物对热应激的反应之间存在相关性。在进食行为方面,40 毫克/天和 80 毫克/天的 CNM 剂量显著减少了进食时间,同时增加了反刍时间。血液分析表明,所有处理的血糖水平都有显著降低,T40 能显著降低胆固醇和甘油三酯 (TG) 水平。此外,补充氯化萘可降低血清丙二醛(MDA)水平,提高超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GPx)活性,表明抗氧化状态得到改善。生理反应受到 CNM 的影响,直肠温度(RT)、皮肤温度(ST)和呼吸频率(RR)显著降低,而脉搏频率(PR)在不同时间间隔内均有所增加,尤其是在 T80 组。本研究表明,补充 CNM 可提高热应激育肥羔羊的生产性能、生理反应和抗氧化状态,突出了其在绵羊养殖中缓解热应激影响的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of dietary curcumin nano-micelles on performance, biological responses, and thermal stress resilience in heat-stressed fattening lambs across varying temperature-humidity index conditions: Implications for climate change

Heat stress poses a significant challenge to sheep farming in arid and semi-arid regions, impacting growth performance, health, and physiological responses. While sheep have innate mechanisms to manage heat stress, prolonged exposure impairs their performance and health. This study evaluated the influence of varying doses of Curcumin Nano-Micelle (CNM) on heat-stressed fattening lambs in northeastern Iran over three months, examining the relationship between CNM doses and growth performance, feeding behavior, physiological responses, immune function, and antioxidant status. Thirty-two crossbred male lambs were included in a completely randomized design with four treatments and eight replications. The experimental treatments were as follows: 1) CTRL: No dietary inclusion of CNM, (control group); 2) T20: Dietary inclusion of 20 mg of CNM per head per day; 3) T40: Dietary inclusion of 40 mg of CNM per head per day; and 4) T80: Dietary inclusion of 80 mg of CNM per head per day. The results revealed that dietary supplementation with 20 and 40 mg of CNM significantly improved live body weight, weight gain, average daily gain (ADG), and feed conversion ratio (FCR) compared to the control treatment. Regression analysis demonstrated quadratic models between growth performance parameters and the Temperature-Humidity Index (THI), indicating a correlation between CNM doses and the animals' responses to heat stress. Regarding eating behavior, CNM doses of 40 and 80 mg/day significantly reduced eating time while increasing ruminating time. Blood analysis indicated significant reductions in glucose levels across all treatments, with T40 significantly reducing both cholesterol and triglyceride (TG) levels. Additionally, CNM supplementation decreased serum malondialdehyde (MDA) levels and increased superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities, indicating enhanced antioxidant status. Physiological responses were influenced by CNM, notably reducing rectal temperature (RT), skin temperature (ST), respiration rate (RR), while pulse rate (PR) increased across various time intervals, particularly in the T80 group. This study demonstrates that CNM supplementation can enhance performance, physiological responses, and antioxidant status in heat-stressed fattening lambs, highlighting its potential to mitigate heat stress effects in sheep farming.

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来源期刊
Journal of thermal biology
Journal of thermal biology 生物-动物学
CiteScore
5.30
自引率
7.40%
发文量
196
审稿时长
14.5 weeks
期刊介绍: The Journal of Thermal Biology publishes articles that advance our knowledge on the ways and mechanisms through which temperature affects man and animals. This includes studies of their responses to these effects and on the ecological consequences. Directly relevant to this theme are: • The mechanisms of thermal limitation, heat and cold injury, and the resistance of organisms to extremes of temperature • The mechanisms involved in acclimation, acclimatization and evolutionary adaptation to temperature • Mechanisms underlying the patterns of hibernation, torpor, dormancy, aestivation and diapause • Effects of temperature on reproduction and development, growth, ageing and life-span • Studies on modelling heat transfer between organisms and their environment • The contributions of temperature to effects of climate change on animal species and man • Studies of conservation biology and physiology related to temperature • Behavioural and physiological regulation of body temperature including its pathophysiology and fever • Medical applications of hypo- and hyperthermia Article types: • Original articles • Review articles
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