水生环境中的氟喹诺酮类抗生素:环境分布、研究现状和生态毒性。

IF 2.1 4区 医学 Q3 CHEMISTRY, MULTIDISCIPLINARY
Drug and Chemical Toxicology Pub Date : 2024-11-01 Epub Date: 2024-06-27 DOI:10.1080/01480545.2024.2362890
Jia Du, Wenfei Huang, Ying Pan, Shaodan Xu, Huanxuan Li, Qinghua Liu
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引用次数: 0

摘要

由于氟喹诺酮类(FQ)抗生素的广泛使用,水生环境中氟喹诺酮类抗生素的存在日益增多,对水生生物造成了负面影响,这一点日益引起人们的关注。本文概述了氟喹诺酮类抗生素在水生环境中的环境分布、来源、归宿以及单一毒性和混合毒性。本文还探讨了 FQ 抗生素在水生生物体内的累积情况,以及它们通过食物链进入人体的情况。研究确定了影响水生环境中 FQ 抗生素存在的关键因素,如代谢特征、理化特征、光照、温度、溶解氧和环境兼容性。FQ 抗生素的混合污染物对生态环境构成了重大风险。此外,本文还批判性地讨论了旨在去除废水中 FQ 抗生素的先进处理技术,重点是高级氧化工艺 (AOP) 和电化学高级氧化工艺 (EAOP)。讨论还包括这些技术在废水处理厂中降解 FQ 抗生素的优势和局限性。论文最后提出了调节和控制 FQ 抗生素的新方法,以帮助制定生态保护措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fluoroquinolone antibiotics in the aquatic environment: environmental distribution, the research status and eco-toxicity.

The increasing presence of fluoroquinolone (FQ) antibiotics in aquatic environments is a growing concern due to their widespread use, negatively impacting aquatic organisms. This paper provides an overview of the environmental distribution, sources, fate, and both single and mixed toxicity of FQ antibiotics in aquatic environments. It also examines the accumulation of FQ antibiotics in aquatic organisms and their transfer into the human body through the food chain. The study identifies critical factors such as metabolism characteristics, physiochemical characteristics, light, temperature, dissolved oxygen, and environmental compatibility that influence the presence of FQ antibiotics in aquatic environments. Mixed pollutants of FQ antibiotics pose significant risks to the ecological environment. Additionally, the paper critically discusses advanced treatment technologies designed to remove FQ antibiotics from wastewater, focusing on advanced oxidation processes (AOPs) and electrochemical advanced oxidation processes (EAOPs). The discussion also includes the benefits and limitations of these technologies in degrading FQ antibiotics in wastewater treatment plants. The paper concludes by proposing new approaches for regulating and controlling FQ antibiotics to aid in the development of ecological protection measures.

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来源期刊
Drug and Chemical Toxicology
Drug and Chemical Toxicology 医学-毒理学
CiteScore
6.00
自引率
3.80%
发文量
99
审稿时长
3 months
期刊介绍: Drug and Chemical Toxicology publishes full-length research papers, review articles and short communications that encompass a broad spectrum of toxicological data surrounding risk assessment and harmful exposure. Manuscripts are considered according to their relevance to the journal. Topics include both descriptive and mechanics research that illustrates the risk assessment implications of exposure to toxic agents. Examples of suitable topics include toxicological studies, which are structural examinations on the effects of dose, metabolism, and statistical or mechanism-based approaches to risk assessment. New findings and methods, along with safety evaluations, are also acceptable. Special issues may be reserved to publish symposium summaries, reviews in toxicology, and overviews of the practical interpretation and application of toxicological data.
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