骨内缺损再生手术的长期成功和影响因素:回顾性队列研究

IF 4.2 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Yan Huang, Xiangying Ouyang, Bei Liu, Jianru Liu, Wenyi Liu, Ying Xie
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Multivariate logistic regressions were performed to identify factors influencing COM‐based long‐term success.ResultsEighty‐one defects in 75 teeth of 33 patients who completed follow‐up (6.5 ± 1.4 years) were included. One tooth was lost. All defects with complete follow‐up exhibited long‐term average CAL gain (3.00 ± 2.00 mm, 95% confidence interval [CI]: 2.56–3.44 mm, <jats:italic>p </jats:italic>&lt; 0.001) and PPD reduction (2.06 ± 1.91 mm, 95% CI: 1.64–2.49 mm, <jats:italic>p </jats:italic>&lt; 0.001). Long‐term success was achieved in 38.8% of IBDs. CAL and PPD values were comparable between 1 year and the last follow‐up. Logistic regression analyses revealed that male sex (odds ratio [OR] = 0.23, 95% CI: 0.07–0.75) and bleeding on probing (BOP) during supportive periodontal therapy (OR = 0.96, 95% CI: 0.94–0.99) were risk factors for long‐term success.ConclusionsRegenerative surgery with DBBM and RM for IBDs can achieve some degree of long‐term success defined by COM. 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引用次数: 0

摘要

背景综合结果测量法(COM)比单一探查测量法更能全面评估再生手术的临床疗效。方法我们回顾性地收集了使用去蛋白牛骨矿物质(DBBM)和可吸收胶原膜(RM)进行骨内缺损(IBD)再生手术患者的数据。比较了基线(术前)、1 年(短期)和最后一次随访(5-10 年)时的 CAL 和 PPD 值。结果 共纳入 33 名完成随访(6.5 ± 1.4 年)的患者的 75 颗牙齿中的 81 处缺损。其中一颗牙齿脱落。所有完成随访的缺损均表现出长期平均 CAL 增加(3.00 ± 2.00 mm,95% 置信区间 [CI]:2.56-3.44 mm,p < 0.001)和 PPD 减少(2.06 ± 1.91 mm,95% CI:1.64-2.49 mm,p < 0.001)。38.8%的 IBD 获得了长期成功。CAL值和PPD值在1年和最后一次随访期间具有可比性。逻辑回归分析表明,男性(几率比[OR] = 0.23,95% CI:0.07-0.75)和牙周支持治疗期间的探诊出血(BOP)(OR = 0.96,95% CI:0.94-0.99)是长期成功的风险因素。临床试验编号:ChiCTR2300069016.
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Long‐term success and influencing factors of regenerative surgery for intra‐bony defects: A retrospective cohort study
BackgroundThe composite outcome measure (COM) more comprehensively assesses the clinical efficacy of regenerative surgery than a single probing measurement. We aimed to assess long‐term success defined by the COM (clinical attachment level [CAL] gain of ≥3 mm and postsurgery probing pocket depth [PPD] ≤ 4 mm) and influencing factors of regenerative surgery using bone substitutes and resorbable collagen membrane (RM) for intra‐bony defects (IBDs).MethodsWe retrospectively collected data from patients who underwent regenerative surgery using deproteinized bovine bone mineral (DBBM) and RM for IBDs. CAL and PPD values were compared at baseline (preoperative), 1 year (short‐term), and at the last follow‐up (5–10 years). Multivariate logistic regressions were performed to identify factors influencing COM‐based long‐term success.ResultsEighty‐one defects in 75 teeth of 33 patients who completed follow‐up (6.5 ± 1.4 years) were included. One tooth was lost. All defects with complete follow‐up exhibited long‐term average CAL gain (3.00 ± 2.00 mm, 95% confidence interval [CI]: 2.56–3.44 mm, p < 0.001) and PPD reduction (2.06 ± 1.91 mm, 95% CI: 1.64–2.49 mm, p < 0.001). Long‐term success was achieved in 38.8% of IBDs. CAL and PPD values were comparable between 1 year and the last follow‐up. Logistic regression analyses revealed that male sex (odds ratio [OR] = 0.23, 95% CI: 0.07–0.75) and bleeding on probing (BOP) during supportive periodontal therapy (OR = 0.96, 95% CI: 0.94–0.99) were risk factors for long‐term success.ConclusionsRegenerative surgery with DBBM and RM for IBDs can achieve some degree of long‐term success defined by COM. However, within this study's limitations, male sex and higher BOP incidence postoperatively are negatively associated with optimal long‐term success.Clinical trial numberChiCTR2300069016.
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来源期刊
Journal of periodontology
Journal of periodontology 医学-牙科与口腔外科
CiteScore
9.10
自引率
7.00%
发文量
290
审稿时长
3-8 weeks
期刊介绍: The Journal of Periodontology publishes articles relevant to the science and practice of periodontics and related areas.
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