在 "失去磅数 "试验中,等热量替代超加工食品与更大的体重减轻相关。

IF 4.2 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Obesity Pub Date : 2024-06-27 DOI:10.1002/oby.24044
Qisi Yao, Carolina D. de Araujo, Filippa Juul, Catherine M. Champagne, George A. Bray, Frank M. Sacks, Maya K. Vadiveloo
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引用次数: 0

摘要

目的:超加工食品(UPFs)摄入量较高与肥胖有关。在这项 "使用新型膳食策略预防超重"(POUNDS)失效试验的二次前瞻性分析中,我们研究了用微量加工食品和烹饪配料(NOVA 1 + 2)替代超量加工食品(NOVA 4)是否与不同的体重变化有关:我们通过对 356 名参与者的子集进行 24 小时膳食回顾,估算了 NOVA 四组的能量摄入百分比(%kcal)。多变量调整替代模型检验了用 NOVA 1 + 2 取代 UPFs 的能量摄入百分比是否与 6 个月后体重、体脂百分比、躯干脂肪和腰围的减少有关;比较了 NOVA 1 + 2 tertiles (T) 之间的参数变化:参与者平均年龄为 52.3 岁,85% 为白人,55% 为女性,58.2% 不吸烟,平均体重指数为 32.7 kg/m2。用 NOVA 1 + 2 取代 10%kcal 的 UPFs 会增加 6 个月的体重(ß = 0.51,95% CI:-0.93 至 -0.09,p = 0.02)、体脂百分比(ß = 2.7,95% CI:-5.10 至 -0.43,p = 0.02)和躯干脂肪减少量(ß = 3.9,95% CI:-7.01 至 -0.70,p = 0.02),但不会减少腰围。NOVA 1 + 2 的 T3 组(-8.33 千克)与 T1 组(-5.32 千克)相比,体重减轻幅度更大(p 结论:NOVA 1 + 2 的 T3 组(-8.33 千克)与 T1 组(-5.32 千克)相比,体重减轻幅度更大:在能量限制条件下,用 NOVA 1 + 2 替代 UPFs 的等热量摄入与略微增加的体重减轻有关。这些适度的研究结果支持开展更多研究,探索 UPF 与能量摄入之外的体重调节机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Isocaloric replacement of ultraprocessed foods was associated with greater weight loss in the POUNDS Lost trial

Isocaloric replacement of ultraprocessed foods was associated with greater weight loss in the POUNDS Lost trial

Objective

Higher intake of ultraprocessed foods (UPFs) is associated with obesity. We examined whether replacing UPFs (NOVA 4) with minimally processed foods and culinary ingredients (NOVA 1 + 2) was associated with differential weight change in this secondary prospective analysis of the Preventing Overweight Using Novel Dietary Strategies (POUNDS) Lost trial.

Methods

We estimated percent energy intake (%kcal) from the four NOVA groups using 24-h dietary recalls in a subset of 356 participants. Multivariable-adjusted substitution models examined whether replacing %kcal from UPFs with NOVA 1 + 2 was associated with greater weight, body fat percentage, trunk fat, and waist circumference reduction at 6 months; changes in parameters were compared among NOVA 1 + 2 tertiles (T).

Results

Participants were on average 52.3 years of age, 85% White, 55% female, and 58.2% nonsmoking, with a mean BMI of 32.7 kg/m2. Replacing 10%kcal of UPFs with NOVA 1 + 2 was associated with greater 6-month weight (ß = 0.51, 95% CI: −0.93 to −0.09, p = 0.02), body fat percentage (ß = 2.7, 95% CI: −5.10 to −0.43, p = 0.02), and trunk fat reduction (ß = 3.9, 95% CI: −7.01 to −0.70, p = 0.02), but not waist circumference reduction. Participants in T3 (−8.33 kg) versus T1 (−5.32 kg) of NOVA 1 + 2 had greater weight loss (p < 0.001).

Conclusions

Isocaloric substitution of UPFs with NOVA 1 + 2 was associated with marginally greater weight loss under energy restriction. These modest findings support more research exploring the mechanisms linking UPFs with body weight regulation beyond energy intake.

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来源期刊
Obesity
Obesity 医学-内分泌学与代谢
CiteScore
11.70
自引率
1.40%
发文量
261
审稿时长
2-4 weeks
期刊介绍: Obesity is the official journal of The Obesity Society and is the premier source of information for increasing knowledge, fostering translational research from basic to population science, and promoting better treatment for people with obesity. Obesity publishes important peer-reviewed research and cutting-edge reviews, commentaries, and public health and medical developments.
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