将红色光生物调节疗法与聚二氧丙酮线结合用于睑板部除皱:随机对照双盲临床试验。

IF 2 3区 物理与天体物理 Q3 BIOCHEMICAL RESEARCH METHODS
Paula Caroline Garcia, Danilo Peron Meireles, João Alberto Fioravante Tassinary, Christiane Pavani
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引用次数: 0

摘要

聚二氧丙酮(PDO)线与其他技术的结合在年轻化方面引起了极大的兴趣。光生物调节(PBM)有可能改善微创年轻化方案后患者的舒适度和恢复情况,还有助于提高这些程序的整体疗效,促进皮肤年轻化的综合方法。这项工作的目的是在一项平行随机假对照试验中,研究同时应用 PDO 线和红色 LED PBM 治疗眉间静态皱纹的效果。40 名 Glogau 衰老分级为 3 级和 4 级、有静态瞥眉皱纹且无明显合并症的人接受了沿瞥眉线施用 PDO 线的治疗。有效的 PBM 组接受 1.35 J 和 630 nm 的红色 LED 光照射,每周两次,共九次,每次 30 天。结果测量包括肿胀评估、真皮厚度和线性超声波 PDO 线降解。使用 PDO 线 24 小时后未发现肿胀,这妨碍了对 PBM 效果的评估。PDO 线诱导真皮增厚;而 PBM 没有增加效果。虽然有些超声波记录无法确定是否存在线头,但各组之间的线头水解情况无明显差异。没有肿胀可能是多种因素造成的,包括术后肿胀评估的时间、操作者使用线的熟练程度和程序特点。没有证据支持 PBM 能增加真皮增厚的观点,但应研究其他光线参数。没有足够数据证明 PBM 能有效控制术后肿胀。将 PBM 与 PDO 线结合使用不会增强真皮增厚,也不会在此处使用的参数下加速线的降解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Combining red photobiomodulation therapy with polydioxanone threads for wrinkle reduction in the glabella region: A randomized, controlled, double-blind clinical trial

Combining red photobiomodulation therapy with polydioxanone threads for wrinkle reduction in the glabella region: A randomized, controlled, double-blind clinical trial

The combination of polydioxanone (PDO) threads with other technologies has garnered significant interest for rejuvenation purposes. Photobiomodulation (PBM) has the potential to improve patient comfort and recovery after minimally invasive rejuvenation protocols and also contribute to the overall efficacy of these procedures, fostering an integrative approach to cutaneous rejuvenation. The objective os this work was to investigate concurrent application of PDO threads and red LED PBM on glabellar static wrinkles, in a parallel randomized sham-controlled trial. Forty individuals with Glogau aging classification levels 3 and 4, static glabellar wrinkles, and no significant comorbidities received PDO threads applied along glabellar line. Effective PBM group received 1.35 J and 630 nm red LED light punctually along threads, twice weekly for nine sessions over 30 days. The outcome measures were swelling assessment, dermal thickness and PDO thread degradation via linear ultrasound. No swelling was detected 24 h post-PDO thread application, hindering PBM effect assessment. PDO threads induced dermal thickening; no added effect with PBM. No significant difference in thread hydrolysis between groups, though some ultrasound records inconclusive on thread presence. The absence of swelling may stem from various factors, including the timing of post-procedure swelling assessment, operator proficiency in thread application, and procedural characteristics. No evidence supports the notion that PBM augments dermal thickening, however other light parameters should be studied. Insufficient data to demonstrate PBM's effectiveness in controlling post-procedure swelling. Combination of PBM with PDO thread application doesn't enhance dermal thickening, nor accelerate thread degradation at the parameters used here.

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来源期刊
Journal of Biophotonics
Journal of Biophotonics 生物-生化研究方法
CiteScore
5.70
自引率
7.10%
发文量
248
审稿时长
1 months
期刊介绍: The first international journal dedicated to publishing reviews and original articles from this exciting field, the Journal of Biophotonics covers the broad range of research on interactions between light and biological material. The journal offers a platform where the physicist communicates with the biologist and where the clinical practitioner learns about the latest tools for the diagnosis of diseases. As such, the journal is highly interdisciplinary, publishing cutting edge research in the fields of life sciences, medicine, physics, chemistry, and engineering. The coverage extends from fundamental research to specific developments, while also including the latest applications.
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