不仅仅是你吃了什么:童年虐待与成人体重指数升高之间的关系综述》。

IF 4.6 3区 医学 Q1 NUTRITION & DIETETICS
Current Nutrition Reports Pub Date : 2024-09-01 Epub Date: 2024-06-26 DOI:10.1007/s13668-024-00558-4
Carmelle Wallace, Richard Krugman
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引用次数: 0

摘要

审查目的:肥胖症是成年人中极为常见的一种病症。越来越多的研究表明,虐待儿童与成人肥胖之间存在显著关系:最新研究表明,各种类型的虐待儿童行为与成年后的体重指数之间存在潜在的剂量反应关系。最新研究还探讨了下丘脑-垂体-肾上腺(HPA)轴和其他激素介质(如性激素结合球蛋白和瘦素)的潜在作用。还有一些研究表明,抑郁、社会经济和环境影响等因素也会介导这种关系。已报道的并发症包括心血管和代谢疾病、糖尿病和胰岛素抵抗。初步研究还表明,虐待对成年肥胖的影响可能存在性别和种族差异。在这篇叙述性综述中,我们总结了现有的工作,描述了不同的儿童虐待类型(身体虐待、性虐待、情感虐待、言语虐待和儿童忽视)及其与成年肥胖的关系、对潜在剂量-反应关系的了解、潜在的中介因素和病理生理学、合并症以及有关性别和种族/民族差异的初步工作。我们回顾了已研究的干预措施的有限数据,最后讨论了对治疗成人肥胖症的临床医生的影响和建议,以及未来潜在的研究方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
More Than What You Eat: A Review on the Association Between Childhood Maltreatment and Elevated Adult BMI.

Purpose of review: Obesity is an overwhelmingly common medical entity seen in the adult population. A growing body of research demonstrates that there is a significant relationship between child maltreatment and adult obesity.

Recent findings: Emerging research demonstrates a potential dose-response relationship between various types of child abuse and adulthood BMI. Recent work also explores the potential role of the hypothalamic-pituitary-adrenal (HPA) axis, and other hormonal mediators such as sex-hormone binding globulin and leptin. There are also studies that suggest factors such as depression and socioeconomic and environmental influences mediate this relationship. Comorbidities that have been reported include cardiovascular and metabolic disease, diabetes, and insulin resistance. Preliminary work also demonstrates potential gender and racial disparities in the effect of abuse on adulthood obesity. In this narrative review, we summarize the existing work describing the different child maltreatment types (physical, sexual, emotional, verbal, and child neglect) and their relation to adult obesity, what is known about a potential dose-response relationship, potential mediators and pathophysiology, comorbidities, and preliminary work on gender and racial/ethnic disparities. We review the limited data on interventions that have been studied, and close with a discussion of implications and suggestions for clinicians who treat adult obesity, as well as potential future research directions.

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来源期刊
Current Nutrition Reports
Current Nutrition Reports Agricultural and Biological Sciences-Food Science
CiteScore
7.70
自引率
2.00%
发文量
59
期刊介绍: This journal aims to provide comprehensive review articles that emphasize significant developments in nutrition research emerging in recent publications. By presenting clear, insightful, balanced contributions by international experts, the journal intends to discuss the influence of nutrition on major health conditions such as diabetes, cardiovascular disease, cancer, and obesity, as well as the impact of nutrition on genetics, metabolic function, and public health. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas across the field. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an Editorial Board of more than 25 internationally diverse members reviews the annual table of contents, suggests topics of special importance to their country/region, and ensures that topics and current and include emerging research.
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