安大略省的髋部骨折率和骨质疏松症治疗:基于人群的回顾性队列研究。

IF 3.1 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Hajar AbuAlrob, George Ioannidis, Susan Jaglal, Andrew Costa, Lauren E Grifith, Lehana Thabane, Jonathan D Adachi, Cathy Cameron, Loretta Hillier, Arthur Lau, Alexandra Papaioannou
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Only 23% of LTC residents at high fracture risk received osteoporosis treatment.</p><p><strong>Purpose: </strong>This population-based study examines hip fracture rate and osteoporosis management among long-term care (LTC) residents > 65 years of age compared to community-dwelling older adults at the time of fracture and admitted to LTC after fracture, in Ontario, Canada.</p><p><strong>Methods: </strong>Healthcare utilization and administrative databases were linked using unique, encoded identifiers from the ICES Data Repository to estimate hip fractures (identified using the Public Health Agency of Canada algorithm and International Classification of Diseases (ICD)-10 codes) and osteoporosis management (pharmacotherapy) among adults > 66 years from April 1, 2014 to March 31, 2018. Sex-specific and age-standardized rates were compared by pre-fracture residency and discharge location (i.e., LTC to LTC, community to LTC, or community to community). 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引用次数: 0

摘要

这项基于人群的研究分析了老年人的髋部骨折率和骨质疏松症治疗率,并根据骨折前的居住地进行了分层。与长期护理中心居民和居住在社区的老年人相比,居住在社区并在骨折后出院到长期护理中心(LTC)的老年人髋部骨折率更高。目的:这项基于人群的研究调查了加拿大安大略省 65 岁以上长期护理(LTC)居民的髋部骨折率和骨质疏松症管理情况,与骨折时居住在社区和骨折后入住 LTC 的老年人进行了比较。方法:使用来自 ICES 数据库的唯一编码标识符对医疗保健利用和行政数据库进行链接,以估算 2014 年 4 月 1 日至 2018 年 3 月 31 日期间年龄大于 66 岁的成年人中的髋部骨折(使用加拿大公共卫生署算法和国际疾病分类 (ICD)-10 代码识别)和骨质疏松症管理(药物治疗)情况。按照骨折前的居住地和出院地点(即从 LTC 到 LTC、从社区到 LTC 或从社区到社区)对性别比率和年龄标准化率进行了比较。骨折风险采用骨折风险量表(FRS)确定:基线(2014/15 年)时,LTC 居民的总体年龄标准化髋部骨折率为每 10,000 人年 223 例(每 10,000 名女性中 173 例,每 10,000 名男性中 157 例),社区到 LTC 队列中为每 10,000 人年 509 例(每 10,000 名女性中 468 例,每 10,000 名男性中 320 例),每 10,000 人年 31.5 例(每 10,000 名女性中 43.1 例,每 10,000 名男性中 25.6 例)。在 5 年的观察期内,与社区到 LTC 组(AAPC = + 2.5 (95% CI - 3.0 to 8.2; p = 0.248))和社区到社区队列(AAPC - 3.8 (95% CI - 6.7 to - 0.7; p = 030))相比,LTC 组髋部骨折的总体年平均百分比变化 (APC) 显著增加(AAPC = + 8.6 (95% CI 5.0 to 12.3; p = 0.004))。然而,在研究期间,社区到长期护理中心组的髋部骨折率仍然较高。有33594名长期护理居民被确定为骨折高危人群(FRS评分4+),其中7777人正在接受治疗(23.3%):总体而言,在长期护理中心和社区居住的成年人中,骨折后入住长期护理中心的髋部骨折率有所上升。然而,在社区居住的成年人中,髋部骨折率却随着时间的推移而下降。在骨折高危人群(FRS4 +)中,观察到骨质疏松症治疗率出现了非显著性增长。长期护理中心的居民骨折风险非常高,需要根据护理目标和预期寿命进行个性化治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Hip fracture rate and osteoporosis treatment in Ontario: A population-based retrospective cohort study.

Hip fracture rate and osteoporosis treatment in Ontario: A population-based retrospective cohort study.

This population-based study analyzes hip fracture and osteoporosis treatment rates among older adults, stratified by place of residence prior to fracture. Hip fracture rates were higher among older adults living in the community and discharged to long-term care (LTC) after fracture, compared to LTC residents and older adults living in the community. Only 23% of LTC residents at high fracture risk received osteoporosis treatment.

Purpose: This population-based study examines hip fracture rate and osteoporosis management among long-term care (LTC) residents > 65 years of age compared to community-dwelling older adults at the time of fracture and admitted to LTC after fracture, in Ontario, Canada.

Methods: Healthcare utilization and administrative databases were linked using unique, encoded identifiers from the ICES Data Repository to estimate hip fractures (identified using the Public Health Agency of Canada algorithm and International Classification of Diseases (ICD)-10 codes) and osteoporosis management (pharmacotherapy) among adults > 66 years from April 1, 2014 to March 31, 2018. Sex-specific and age-standardized rates were compared by pre-fracture residency and discharge location (i.e., LTC to LTC, community to LTC, or community to community). Fracture risk was determined using the Fracture Risk Scale (FRS).

Results: At baseline (2014/15), the overall age-standardized hip fracture rate among LTC residents was 223 per 10,000 person-years (173 per 10,000 females and 157 per 10,000 males), 509 per 10,000 person-years (468 per 10,000 females and 320 per 10,000 males) among the community to LTC cohort, and 31.5 per 10,000 person-years (43.1 per 10,000 females and 25.6 per 10,000 males). During the 5-year observation period, the overall annual average percent change (APC) for hip fracture increased significantly in LTC (AAPC =  + 8.6 (95% CI 5.0 to 12.3; p = 0.004) compared to the community to LTC group (AAPC =  + 2.5 (95% CI - 3.0 to 8.2; p = 0.248)) and the community-to-community cohort (AAPC - 3.8 (95% CI - 6.7 to - 0.7; p = 030)). However, hip fracture rate remained higher in the community to LTC group over the study period. There were 33,594 LTC residents identified as high risk of fracture (FRS score 4 +), of which 7777 were on treatment (23.3%).

Conclusion: Overall, hip fracture rates have increased in LTC and among community-dwelling adults admitted to LTC after fracture. However, hip fracture rates among community-dwelling adults have decreased over time. A non-significant increase in osteoporosis treatment rates was observed among LTC residents at high risk of fracture (FRS4 +). Residents in LTC are at very high risk for fracture and require individualized based on goals of care and life expectancy.

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来源期刊
Archives of Osteoporosis
Archives of Osteoporosis ENDOCRINOLOGY & METABOLISMORTHOPEDICS -ORTHOPEDICS
CiteScore
5.50
自引率
10.00%
发文量
133
期刊介绍: Archives of Osteoporosis is an international multidisciplinary journal which is a joint initiative of the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA. The journal will highlight the specificities of different regions around the world concerning epidemiology, reference values for bone density and bone metabolism, as well as clinical aspects of osteoporosis and other bone diseases.
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