7特斯拉磁共振成像对比增强三维脂肪饱和T1-MPRAGE检查中Rathke裂隙和其他偶然垂体发现的患病率。

Mikael Mir, Nathaniel P Miller, Matthew White, Wendy Elvandahl, Ayca Ersen Danyeli, Can Özütemiz
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引用次数: 0

摘要

背景和目的:临床 7T 磁共振成像(MRI)对比增强三维脂肪饱和 T1-MPRAGE(C+3D-FS-T1 MPRAGE)在腺嗜酸性粒细胞/神经嗜酸性粒细胞边界的垂体中反复观察到裂隙样非增强低密度。我们的首要目标是评估这一发现的普遍性。我们的次要目标是评估垂体其他偶发病变、MRI 伪影的频率及其对垂体在 7T C+3D-FS-T1 MPRAGE 上成像的影响。对每个病例的 C+3D-FS-T1 MPRAGE 进行评估,以确定是否存在裂隙样垂体低密度、垂体肿块和伪影。如果存在随访检查,则对其进行评估。计算了每项发现的平均发生率,并对年龄和性别进行了描述性统计:结果:66%的 7T 磁共振成像中存在裂隙样低密度。在性别(P = .39)和年龄(P = .32)方面,"类裂隙存在 "组和 "类裂隙不存在 "组之间无明显差异。在后续的磁共振成像中,3/3 的 7T 患者、1/12 的 3T 患者和 1/5 的 1.5T 患者出现了裂隙样低密度。22%的患者发现肿块,75%无肿块,3%不确定。在 "类裂隙存在 "组中有 18 人(27%)发现肿块,在 "类裂隙缺失 "组中有 4 人(13%)发现肿块。最常见的肿块类型是:"类裂隙存在 "组中有 7 例(31.8%)患者的 Rathke 裂隙囊肿(RCC)、6 例(27.3%)患者的 "RCC vs. 夹带 CSF "和 6 例(22.2%)患者的微腺瘤。类裂隙存在 "组和 "类裂隙不存在 "组的肿块类型无明显差异(P = 0.23)。使用 C+3D-FS-T1 MPRAGE 时,易感性和/或运动伪影普遍存在(54%)。在 "类裂隙存在 "组中,无伪影扫描的频率明显更高(P =.03):7T磁共振成像的C+3D-FS-T1 MPRAGE上经常出现裂隙样非增强低密度,这很可能代表正常胚胎的Rathke氏裂隙残留,在较低场强的磁共振成像中无法看到。椎间盘中常见的是易感性和运动伪影。它们可能会影响图像质量,7T 下的伪影可能会导致低估 Rathke 裂隙和其他偶然发现的患病率:缩写:C+3D-FS-T 1MPRAGE = 对比度增强 3D 脂肪饱和 T1 磁准备快速梯度回波成像;RCC = Rathke 裂囊。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of Rathke Cleft and Other Incidental Pituitary Gland Findings on Contrast-Enhanced 3D Fat-Saturated T1 MPRAGE at 7T MRI.

Background and purpose: A cleftlike nonenhancing hypointensity was observed repeatedly in the pituitary gland at the adenohypophysis/neurohypophysis border on contrast-enhanced 3D fat-saturated T1-MPRAGE using clinical 7T MRI. Our primary goal was to assess the prevalence of this finding. The secondary goals were to evaluate the frequency of other incidental pituitary lesions, MRI artifacts, and their effect on pituitary imaging on the contrast-enhanced 3D fat-saturated T1 MPRAGE at 7T.

Materials and methods: One hundred patients who underwent 7T neuroimaging between October 27, 2021, and August 10, 2023, were included. Each case was evaluated for cleftlike pituitary hypointensity, pituitary masses, and artifacts on contrast-enhanced 3D fat-saturated T1 MPRAGE. Follow-up examinations were evaluated if present. The average prevalence for each finding was calculated, as were descriptive statistics for age and sex.

Results: A cleftlike hypointensity was present in 66% of 7T MRIs. There were no significant differences between the "cleftlike present" and "cleftlike absent" groups regarding sex (P = .39) and age (P = .32). The cleftlike hypointensity was demonstrated on follow-up MRIs in 3/3 patients with 7T, 1/12 with 3T, and 1/5 with 1.5T. A mass was found in 22%, while 75% had no mass and 3% were indeterminate. A mass was found in 18 (27%) of the cleftlike present and 4 (13%) of the cleftlike absent groups. The most common mass types were Rathke cleft cyst in 7 (31.8%) patients, "Rathke cleft cyst versus entrapped CSF" in 6 (27.3%), and microadenoma in 6 (22.2%) in the cleftlike present group. There were no significant differences in the mass types between the cleftlike present and cleftlike absent groups (P = .23). Susceptibility and/or motion artifacts were frequent using contrast-enhanced 3D fat-saturated T1 MPRAGE (54%). Artifact-free scans were significantly more frequent in the cleftlike present group (P = .03).

Conclusions: A cleftlike nonenhancing hypointensity was frequently seen on the contrast-enhanced 3D fat-saturated T1 MPRAGE images at 7T MRI, which most likely represents a normal embryologic Rathke cleft remnant and cannot be seen in lower-field-strength MRIs. Susceptibility and motion artifacts are common in the sella. They may affect image quality, and the artifacts at 7T may lead to an underestimation of the prevalence of the Rathke cleft and other incidental findings.

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