外阴有蒂肿瘤

IF 1.1 4区医学 Q4 DERMATOLOGY

American Journal of Dermatopathology Pub Date : 2024-10-01 Epub Date: 2024-06-14 DOI:10.1097/DAD.0000000000002764

Ziyuan Zeng, Xia Xiong, Zongjunlin Liu, Qirong Lei, Yuanmin He

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引用次数: 0

摘要

摘要：乳腺外Paget病（EMPD）是一种罕见的皮肤恶性肿瘤，通常在会阴等分泌腺丰富的部位表现为湿疹样病变。在此，我们报告了一例 65 岁女性的 EMPD 病例，患者表现为突出的有蒂肿瘤。尽管最初被误诊和误治，但活检证实了 EMPD 的浸润。手术切除后，患者出现脑转移，预后不佳。EMPD的发病机制尚不清楚，但区分原发性和继发性对预后和治疗至关重要。我们的病例强调了识别非典型 EMPD 表现以及时干预和改善预后的重要性。

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Pedunculated Neoplasm of the Vulva.

Abstract: Extramammary Paget disease (EMPD) is a rare cutaneous malignancy, typically presenting as eczema-like lesions in areas rich in apocrine glands such as the perineum. Here, we report a case of EMPD presenting as a prominent pedunculated neoplasm in a 65-year-old woman. Despite initial misdiagnosis and treatment, biopsy confirmed EMPD infiltration. Following surgical excision, the patient developed brain metastases, indicating a poor prognosis. EMPD's pathogenesis remains unclear, but distinguishing primary from secondary forms is crucial for prognosis and treatment. Our case underscores the importance of recognizing atypical EMPD presentations for timely intervention and improved outcomes.

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来源期刊

American Journal of Dermatopathology 医学-皮肤病学

CiteScore

1.80

自引率

9.10%

发文量

453

审稿时长

3 months

期刊介绍： The American Journal of Dermatopathology offers outstanding coverage of the latest diagnostic approaches and laboratory techniques, as well as insights into contemporary social, legal, and ethical concerns. Each issue features review articles on clinical, technical, and basic science advances and illuminating, detailed case reports. With the The American Journal of Dermatopathology you''ll be able to: -Incorporate step-by-step coverage of new or difficult-to-diagnose conditions from their earliest histopathologic signs to confirmatory immunohistochemical and molecular studies. -Apply the latest basic science findings and clinical approaches to your work right away. -Tap into the skills and expertise of your peers and colleagues the world over peer-reviewed original articles, "Extraordinary cases reports", coverage of practical guidelines, and graphic presentations. -Expand your horizons through the Journal''s idea-generating forum for debating controversial issues and learning from preeminent researchers and clinicians