在过渡性护理中对幼年特发性关节炎进行疾病活动评估。

IF 1.2 Q4 RHEUMATOLOGY
F La Torre, C Coppola, M G Anelli, F Cacciapaglia, G Lopalco, F Cardinale, F Iannone
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引用次数: 0

摘要

目的:衡量成年期和儿童期慢性关节炎疾病活动度的指标是不同的。因此,评估幼年特发性关节炎(JIA)年轻患者的疾病状况可能很棘手,尤其是在向成人护理过渡的过程中。我们的研究旨在评估在过渡护理期间,在测量幼年特发性关节炎患者的疾病活动度时,成人评分与幼年评分之间的相关程度:我们使用青少年关节炎疾病活动度评分 71 (JADAS71)、临床 JADAS、成人疾病活动度评分 (DAS28)、简化疾病活动度指数 (SDAI) 和临床疾病活动度指数 (CDAI) 对过渡性护理中的 JIA 患者的疾病活动度进行了评估。我们招募了首次过渡就诊时年龄大于 16 岁的患者,并在基线和 12 个月时对其疾病活动度进行了评估。我们进行了回归分析,以估计不同指数之间的一致程度:我们共招募了26名JIA患者,其中11人为多关节型(42.3%),15人为少关节型(53.1%)。确诊时的平均年龄为(7.7±3.9)岁,首次评估时的年龄为(20.9±3.7)岁。JADAS71和DAS28之间的相关性为r2=0.69,JADAS71和SDAI之间的相关性为r2=0.86,JADAS71和CDAI之间的相关性为r2=0.81:结论:SDAI 和 JADAS71 的相关性最好,但有少数患者的疾病活动水平不尽相同。在这一领域还需要对更多患者进行新的前瞻性研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Disease activity assessment for juvenile idiopathic arthritis in transitional care.

Objective: The indices to measure disease activity of chronic arthritis in adulthood and childhood are different. Therefore, assessing the status of the disease in young patients with juvenile idiopathic arthritis (JIA) can be tricky, especially when the transition to adult care is ongoing. The aim of our study was to assess the level of correlation between adult and juvenile scores in the measurement of disease activity in JIA patients during transitional care.

Methods: We estimated the disease activity by using the Juvenile Arthritis Disease Activity Score 71 (JADAS71), clinical JADAS, adult Disease Activity Score (DAS28), Simplified Disease Activity Index (SDAI), and Clinical Disease Activity Index (CDAI) in JIA patients in transitional care. We enrolled patients older than 16 years at the time of the first transition visit, and disease activity was assessed at baseline and 12 months. Regression analyses were carried out to estimate the level of agreement among the different indices.

Results: We recruited 26 patients with JIA; 11 patients were polyarticular (42.3%) and 15 patients were oligoarticular (53.1%). The mean age at diagnosis was 7.7±3.9 years and the age at the first evaluation was 20.9±3.7 years. The correlation between JADAS71 and DAS28 was r2=0.69, r2=0.86 between JADAS71 and SDAI, and r2=0.81 between JADAS71 and CDAI.

Conclusions: SDAI and JADAS71 showed the best correlation, but a few patients were not captured at the same level of disease activity. New prospective studies with a larger number of patients will be needed in this field.

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来源期刊
Reumatismo
Reumatismo RHEUMATOLOGY-
CiteScore
2.10
自引率
7.10%
发文量
20
审稿时长
10 weeks
期刊介绍: Reumatismo is the official Journal of the Italian Society of Rheumatology (SIR). It publishes Abstracts and Proceedings of Italian Congresses and original papers concerning rheumatology. Reumatismo is published quarterly and is sent free of charge to the Members of the SIR who regularly pay the annual fee. Those who are not Members of the SIR as well as Corporations and Institutions may also subscribe to the Journal.
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