通过 Solve-RD 罕见疾病模型和机制网络（RDMM-欧洲）进行模型匹配。

IF 5.9 3区农林科学 Q1 VETERINARY SCIENCES

Lab Animal Pub Date : 2024-06-24 DOI:10.1038/s41684-024-01395-2

Kornelia Ellwanger, Julie A. Brill, Elke de Boer, Stephanie Efthymiou, Ype Elgersma, Marynelle Icmat, François Lecoquierre, Amanda G. Lobato, Manuela Morleo, Michela Ori, Ashleigh E. Schaffer, Antonio Vitobello, Sara Wells, Binnaz Yalcin, R. Grace Zhai, Marc Sturm, Birte Zurek, Holm Graessner, Eva Bermejo-Sánchez, Teresinha Evangelista, Nicoline Hoogerbrugge, Vincenzo Nigro, Rebecca Schüle, Alain Verloes, Han Brunner, Philippe M. Campeau, Paul Lasko, Olaf Riess

{"title":"通过 Solve-RD 罕见疾病模型和机制网络（RDMM-欧洲）进行模型匹配。","authors":"Kornelia Ellwanger, Julie A. Brill, Elke de Boer, Stephanie Efthymiou, Ype Elgersma, Marynelle Icmat, François Lecoquierre, Amanda G. Lobato, Manuela Morleo, Michela Ori, Ashleigh E. Schaffer, Antonio Vitobello, Sara Wells, Binnaz Yalcin, R. Grace Zhai, Marc Sturm, Birte Zurek, Holm Graessner, Eva Bermejo-Sánchez, Teresinha Evangelista, Nicoline Hoogerbrugge, Vincenzo Nigro, Rebecca Schüle, Alain Verloes, Han Brunner, Philippe M. Campeau, Paul Lasko, Olaf Riess","doi":"10.1038/s41684-024-01395-2","DOIUrl":null,"url":null,"abstract":"In biomedical research, particularly for rare diseases (RDs), there is a critical need for model organisms to unravel the mechanistic basis of diseases, perform biomarker studies and develop potential therapeutic interventions. Within Solve-RD, an EU-funded research project with the aim of solving large numbers of previously unsolved RDs, the European Rare Disease Models & Mechanisms Network (RDMM-Europe) has been established.","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 7","pages":"161-165"},"PeriodicalIF":5.9000,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11216991/pdf/","citationCount":"0","resultStr":"{\"title\":\"Model matchmaking via the Solve-RD Rare Disease Models & Mechanisms Network (RDMM-Europe)\",\"authors\":\"Kornelia Ellwanger, Julie A. Brill, Elke de Boer, Stephanie Efthymiou, Ype Elgersma, Marynelle Icmat, François Lecoquierre, Amanda G. Lobato, Manuela Morleo, Michela Ori, Ashleigh E. Schaffer, Antonio Vitobello, Sara Wells, Binnaz Yalcin, R. Grace Zhai, Marc Sturm, Birte Zurek, Holm Graessner, Eva Bermejo-Sánchez, Teresinha Evangelista, Nicoline Hoogerbrugge, Vincenzo Nigro, Rebecca Schüle, Alain Verloes, Han Brunner, Philippe M. Campeau, Paul Lasko, Olaf Riess\",\"doi\":\"10.1038/s41684-024-01395-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In biomedical research, particularly for rare diseases (RDs), there is a critical need for model organisms to unravel the mechanistic basis of diseases, perform biomarker studies and develop potential therapeutic interventions. Within Solve-RD, an EU-funded research project with the aim of solving large numbers of previously unsolved RDs, the European Rare Disease Models & Mechanisms Network (RDMM-Europe) has been established.\",\"PeriodicalId\":17936,\"journal\":{\"name\":\"Lab Animal\",\"volume\":\"53 7\",\"pages\":\"161-165\"},\"PeriodicalIF\":5.9000,\"publicationDate\":\"2024-06-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11216991/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Lab Animal\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.nature.com/articles/s41684-024-01395-2\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lab Animal","FirstCategoryId":"97","ListUrlMain":"https://www.nature.com/articles/s41684-024-01395-2","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}

引用次数: 0

摘要

在生物医学研究中，尤其是在罕见病（RDs）的研究中，亟需模型生物来揭示疾病的机理基础、进行生物标记物研究和开发潜在的治疗干预措施。Solve-RD 是一个由欧盟资助的研究项目，旨在解决大量以前未解决的罕见病问题，在该项目范围内，建立了欧洲罕见病模型& 机制网络（RDMM-Europe）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Model matchmaking via the Solve-RD Rare Disease Models & Mechanisms Network (RDMM-Europe)

查看原文本刊更多论文

Model matchmaking via the Solve-RD Rare Disease Models & Mechanisms Network (RDMM-Europe)

In biomedical research, particularly for rare diseases (RDs), there is a critical need for model organisms to unravel the mechanistic basis of diseases, perform biomarker studies and develop potential therapeutic interventions. Within Solve-RD, an EU-funded research project with the aim of solving large numbers of previously unsolved RDs, the European Rare Disease Models & Mechanisms Network (RDMM-Europe) has been established.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Lab Animal 农林科学-兽医学

CiteScore

0.60

自引率

2.90%

发文量

181

审稿时长

>36 weeks

期刊介绍： LabAnimal is a Nature Research journal dedicated to in vivo science and technology that improves our basic understanding and use of model organisms of human health and disease. In addition to basic research, methods and technologies, LabAnimal also covers important news, business and regulatory matters that impact the development and application of model organisms for preclinical research. LabAnimal's focus is on innovative in vivo methods, research and technology covering a wide range of model organisms. Our broad scope ensures that the work we publish reaches the widest possible audience. LabAnimal provides a rigorous and fair peer review of manuscripts, high standards for copyediting and production, and efficient publication.