丹麦农村地区鼻衄的风险因素:根据 Lolland-Falster 健康研究数据进行的横断面人口调查。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2024-06-24 DOI:10.1007/s00405-024-08762-2
Lisette Hvid Hovgaard, Casper Grønlund, Preben Homøe
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引用次数: 0

摘要

目的:鼻衄是一种常见病,约有 60% 的人一生中会患上鼻衄,其中 6% 的人需要就医。在医疗保健系统之外,人们对鼻衄的流行病学和风险因素知之甚少。本研究旨在利用洛兰-法尔斯特健康研究(LOFUS)的数据,调查鼻衄在丹麦农村人口中的发病率和风险因素:我们根据 LOFUS 的数据进行了一项横断面调查,LOFUS 是一项基于家庭的前瞻性队列研究,研究对象是丹麦的洛兰-法尔斯特农村地区。我们招募了 10,065 名参与者(≥ 50 岁),并收集了有关人口统计学、合并症、药物治疗、生活方式因素和实验室参数的数据。采用逻辑回归法检验鼻衄与不同风险因素之间的相关性:共有 5.3% 的参与者在过去 30 天内曾有过鼻衄经历,7.9% 的参与者曾因鼻衄就医。我们发现了一些与鼻衄发生几率增加明显相关的因素,如男性、50-59 岁年龄组、高体重指数(大于 25)、过敏、糖尿病、高血压、动脉粥样硬化、心绞痛和抗凝治疗。自我报告健康状况极佳或良好与鼻衄发生几率明显降低相关:本研究全面概述了医疗保健系统外鼻衄的流行率和风险因素。我们的研究表明,针对这些风险因素采取预防措施可降低该人群鼻衄的发病率和严重程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Risk factors of epistaxis in rural Denmark: a cross-sectional population-based survey of data from the Lolland-Falster health study.

Purpose: Epistaxis is a common condition that affects about 60% of the population in their lifetime, with 6% needing medical attention. Little is known about the epidemiology and risk factors of epistaxis outside the health care system. This study aimed to investigate the prevalence and risk factors of epistaxis in a rural Danish population using data from the Lolland-Falster Health Study (LOFUS).

Methods: We conducted a cross-sectional survey based on data from LOFUS, a household-based, prospective cohort study in the rural provincial area of Lolland-Falster, Denmark. We enrolled 10,065 participants (≥ 50 years) and collected data on demographics, comorbidities, medication, lifestyle factors, and laboratory parameters. Logistic regressions were used to test for correlations between epistaxis and different risk factors.

Results: In total 5.3% of the participants had experienced epistaxis within the past 30 days, and 7.9% had sought medical attention for epistaxis at some point in their lives. We identified several factors that were significantly correlated with increased odds of epistaxis, such as male gender, age group 50-59 years, high BMI (> 25), allergy, diabetes, hypertension, atherosclerosis, angina, and anticoagulant treatment. Excellent or good self-reported health was correlated to significantly lower odds of epistaxis.

Conclusion: This study provides a comprehensive overview of the prevalence and risk factors of epistaxis outside the health care system. Our study suggests that preventive measures targeting these risk factors may reduce the incidence and severity of epistaxis in this population.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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