A 型肉毒杆菌神经毒素和皮肤填充剂注射的罕见和新型并发症。

IF 2.3 4区 医学 Q2 DERMATOLOGY
Clinics in dermatology Pub Date : 2024-11-01 Epub Date: 2024-06-22 DOI:10.1016/j.clindermatol.2024.06.023
Marina Landau, Jerome Klein, Frank Rosengaus Leizgold, George Kroumpouzos
{"title":"A 型肉毒杆菌神经毒素和皮肤填充剂注射的罕见和新型并发症。","authors":"Marina Landau, Jerome Klein, Frank Rosengaus Leizgold, George Kroumpouzos","doi":"10.1016/j.clindermatol.2024.06.023","DOIUrl":null,"url":null,"abstract":"<p><p>Botulinum neurotoxin type A (BoNTA) and filler injection procedures usually provide predicted outcomes with a low incidence of complications. Most of the complications after these procedures have been extensively discussed. In this study, we report on these injectables' less well-known, recently reported, and novel complications and attempt to clarify the underlying mechanisms. Counterfeit or mishandled BoNTA has been associated with botulism. BoNTA has been linked to uncommon complications, including morphea-like lesions, nontuberculous mycobacterial infections, vascular occlusion, and pseudoaneurysm of the superficial temporal artery. Unusual complications from filler injection include nonscarring alopecia, intraoral necrosis, nontuberculous mycobacterial infections, xanthelasma-like reactions, intracranial perforation, and pneumosinus dilatans. Post-BoNTA injection nodules and filler infection from bone destruction due to cocaine use are new complications. These complications pose a challenge for diagnosis and treatment. This publication aims to assist in promptly identifying and managing these rare and novel complications when necessary.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":"701-708"},"PeriodicalIF":2.3000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rare and novel complications of botulinum neurotoxin type A and dermal filler injections.\",\"authors\":\"Marina Landau, Jerome Klein, Frank Rosengaus Leizgold, George Kroumpouzos\",\"doi\":\"10.1016/j.clindermatol.2024.06.023\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Botulinum neurotoxin type A (BoNTA) and filler injection procedures usually provide predicted outcomes with a low incidence of complications. Most of the complications after these procedures have been extensively discussed. In this study, we report on these injectables' less well-known, recently reported, and novel complications and attempt to clarify the underlying mechanisms. Counterfeit or mishandled BoNTA has been associated with botulism. BoNTA has been linked to uncommon complications, including morphea-like lesions, nontuberculous mycobacterial infections, vascular occlusion, and pseudoaneurysm of the superficial temporal artery. Unusual complications from filler injection include nonscarring alopecia, intraoral necrosis, nontuberculous mycobacterial infections, xanthelasma-like reactions, intracranial perforation, and pneumosinus dilatans. Post-BoNTA injection nodules and filler infection from bone destruction due to cocaine use are new complications. These complications pose a challenge for diagnosis and treatment. This publication aims to assist in promptly identifying and managing these rare and novel complications when necessary.</p>\",\"PeriodicalId\":10358,\"journal\":{\"name\":\"Clinics in dermatology\",\"volume\":\" \",\"pages\":\"701-708\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinics in dermatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.clindermatol.2024.06.023\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/6/22 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinics in dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.clindermatol.2024.06.023","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/22 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

A 型肉毒杆菌毒素(BoNTA)和填充剂注射程序通常可提供预期的效果,并发症发生率较低。这些手术后的大多数并发症已被广泛讨论过。在本研究中,我们报告了这些注射剂不太为人所知的、最近报道的和新出现的并发症,并试图阐明其根本机制。假冒或处理不当的 BoNTA 与肉毒中毒有关。此外,BoNTA 还与不常见的并发症有关,包括病变样病变、非结核分枝杆菌感染、血管闭塞和颞浅动脉假性动脉瘤。注射填充剂引起的异常并发症包括非瘢痕性脱发、口腔内坏死、非结核分枝杆菌感染、黄褐斑样反应、颅内穿孔和扩张性肺病。使用可卡因导致骨质破坏引起的注射后结节和填充物感染是新的并发症。这些并发症给诊断和治疗带来了挑战。本刊物旨在帮助人们在必要时及时发现和处理这些罕见的新型并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rare and novel complications of botulinum neurotoxin type A and dermal filler injections.

Botulinum neurotoxin type A (BoNTA) and filler injection procedures usually provide predicted outcomes with a low incidence of complications. Most of the complications after these procedures have been extensively discussed. In this study, we report on these injectables' less well-known, recently reported, and novel complications and attempt to clarify the underlying mechanisms. Counterfeit or mishandled BoNTA has been associated with botulism. BoNTA has been linked to uncommon complications, including morphea-like lesions, nontuberculous mycobacterial infections, vascular occlusion, and pseudoaneurysm of the superficial temporal artery. Unusual complications from filler injection include nonscarring alopecia, intraoral necrosis, nontuberculous mycobacterial infections, xanthelasma-like reactions, intracranial perforation, and pneumosinus dilatans. Post-BoNTA injection nodules and filler infection from bone destruction due to cocaine use are new complications. These complications pose a challenge for diagnosis and treatment. This publication aims to assist in promptly identifying and managing these rare and novel complications when necessary.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Clinics in dermatology
Clinics in dermatology 医学-皮肤病学
CiteScore
4.60
自引率
7.40%
发文量
106
审稿时长
3 days
期刊介绍: Clinics in Dermatology brings you the most practical and comprehensive information on the treatment and care of skin disorders. Each issue features a Guest Editor and is devoted to a single timely topic relating to clinical dermatology. Clinics in Dermatology provides information that is... • Clinically oriented -- from evaluation to treatment, Clinics in Dermatology covers what is most relevant to you in your practice. • Authoritative -- world-renowned experts in the field assure the high-quality and currency of each issue by reporting on their areas of expertise. • Well-illustrated -- each issue is complete with photos, drawings and diagrams to illustrate points and demonstrate techniques.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信