反应性抑制控制先于明显的口吃事件

IF 3.6 Q1 LINGUISTICS
Neurobiology of Language Pub Date : 2024-06-03 eCollection Date: 2024-01-01 DOI:10.1162/nol_a_00138
Joan Orpella, Graham Flick, M Florencia Assaneo, Ravi Shroff, Liina Pylkkänen, David Poeppel, Eric S Jackson
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引用次数: 0

摘要

研究表明,口吃者与非口吃者流利说话的神经功能差异。而关于口吃与流利说话的基础过程的研究则少得多。此外,尽管口吃言语发生前的认知过程也有贡献,但大部分研究都集中在言语运动过程上。我们使用 MEG 测试了在口吃言语发生前触发反应性抑制控制的假设。29 名口吃者完成了一项延迟反应任务,该任务的特点是提示(在 "开始 "提示之前)即将要求他们说出一个结巴或流利的单词。与我们的假设一致的是,我们观察到,在结巴与流利发音之前,来自右侧前辅助运动区(R-preSMA)--一个与反应性抑制控制有关的区域--的β功率增加了。口吃试验和流利试验之间的β功率差异与口吃严重程度相关,参与者口吃试验的百分比随R-preSMA中β功率的增加而呈指数增长。在提示之后,R-preSMA 中的逐次试验贝塔功率调节可预测试验是口吃还是流利。口吃试验还与延迟开始说话有关,这表明言语运动系统的整体减慢或冻结可能是抑制控制的结果。事后分析表明,与研究人员辅助的预期词相比,独立产生的预期词与更大的β功率和更多的口吃有关,这表明自我感知的口吃可能性(即预期)与抑制控制之间存在关系。这项研究通过描述明显口吃事件发生前的认知过程,提供了口吃的神经认知解释。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Reactive Inhibitory Control Precedes Overt Stuttering Events.

Research points to neurofunctional differences underlying fluent speech between stutterers and non-stutterers. Considerably less work has focused on processes that underlie stuttered vs. fluent speech. Additionally, most of this research has focused on speech motor processes despite contributions from cognitive processes prior to the onset of stuttered speech. We used MEG to test the hypothesis that reactive inhibitory control is triggered prior to stuttered speech. Twenty-nine stutterers completed a delayed-response task that featured a cue (prior to a go cue) signaling the imminent requirement to produce a word that was either stuttered or fluent. Consistent with our hypothesis, we observed increased beta power likely emanating from the right pre-supplementary motor area (R-preSMA)-an area implicated in reactive inhibitory control-in response to the cue preceding stuttered vs. fluent productions. Beta power differences between stuttered and fluent trials correlated with stuttering severity and participants' percentage of trials stuttered increased exponentially with beta power in the R-preSMA. Trial-by-trial beta power modulations in the R-preSMA following the cue predicted whether a trial would be stuttered or fluent. Stuttered trials were also associated with delayed speech onset suggesting an overall slowing or freezing of the speech motor system that may be a consequence of inhibitory control. Post-hoc analyses revealed that independently generated anticipated words were associated with greater beta power and more stuttering than researcher-assisted anticipated words, pointing to a relationship between self-perceived likelihood of stuttering (i.e., anticipation) and inhibitory control. This work offers a neurocognitive account of stuttering by characterizing cognitive processes that precede overt stuttering events.

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来源期刊
Neurobiology of Language
Neurobiology of Language Social Sciences-Linguistics and Language
CiteScore
5.90
自引率
6.20%
发文量
32
审稿时长
17 weeks
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