瞳孔测量法是眼球优势可塑性的指标。

IF 1.5 4区 心理学 Q4 NEUROSCIENCES
Miriam Acquafredda, Paola Binda
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引用次数: 0

摘要

对视力正常的成年人进行短期单眼视力剥夺会产生短暂的眼球优势转移,从而增强被剥夺视力的那只眼睛的视力。这种效应已通过知觉测试和生理记录得到证实,但以前的研究还没有同时测量生理反应和剥夺的知觉效应。在这里,我们提出了一种综合实验范式,它结合了双眼对抗和瞳孔测量法,引入了眼优势可塑性的客观生理指标,并与知觉测试同时进行。十名参与者报告了双眼对抗的知觉动态,同时我们测量了瞳孔直径。刺激物分别为白色和黑色圆盘,单眼呈现。通过在优势眼上贴一个半透明的眼罩,在单眼被剥夺 2 小时之前和之后,我们对竞争动态和瞳孔大小痕迹进行了比较。与之前的研究一致,我们观察到单眼剥夺增强了被剥夺眼的信号,从而提高了眼优势。与之前的研究一致,我们还观察到瞳孔大小发生了微妙但系统的变化,这种变化跟踪了黑白盘独占优势阶段的交替。在单眼剥夺后,这些瞳孔大小调节的幅度增大,这与剥夺后被剥夺眼的增强和眼支配作用的增强是一致的。这提供了证据,证明剥夺影响了单眼视觉刺激的有效强度,连贯地影响了知觉报告以及瞳孔直径的自动和无意识调节。我们的研究结果表明,双目对抗和瞳孔测量相结合的范例为了解剥夺效应的生理机制提供了新的视角。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pupillometry indexes ocular dominance plasticity

Short-term monocular deprivation in normally sighted adult humans produces a transient shift of ocular dominance, boosting the deprived eye. This effect has been documented with both perceptual tests and through physiological recordings, but no previous study simultaneously measured physiological responses and the perceptual effects of deprivation. Here we propose an integrated experimental paradigm that combines binocular rivalry with pupillometry, to introduce an objective physiological index of ocular dominance plasticity, acquired concurrently with perceptual testing. Ten participants reported the perceptual dynamics of binocular rivalry, while we measured pupil diameter. Stimuli were a white and a black disk, each presented monocularly. Rivalry dynamics and pupil-size traces were compared before and after 2 h of monocular deprivation, achieved by applying a translucent patch over the dominant eye. Consistent with prior research, we observed that monocular deprivation boosts the deprived-eye signal and consequently increases ocular dominance. In line with previous studies, we also observed subtle but systematic modulations of pupil size that tracked alternations between exclusive dominance phases of the black or white disk. Following monocular deprivation, the amplitude of these pupil-size modulations increased, which is consistent with the post-deprivation boost of the deprived eye and the increase of ocular dominance. This provides evidence that deprivation impacts the effective strength of monocular visual stimuli, coherently affecting perceptual reports and the automatic and unconscious regulation of pupil diameter. Our results show that a combined paradigm of binocular rivalry and pupillometry gives new insights into the physiological mechanisms underlying deprivation effects.

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来源期刊
Vision Research
Vision Research 医学-神经科学
CiteScore
3.70
自引率
16.70%
发文量
111
审稿时长
66 days
期刊介绍: Vision Research is a journal devoted to the functional aspects of human, vertebrate and invertebrate vision and publishes experimental and observational studies, reviews, and theoretical and computational analyses. Vision Research also publishes clinical studies relevant to normal visual function and basic research relevant to visual dysfunction or its clinical investigation. Functional aspects of vision is interpreted broadly, ranging from molecular and cellular function to perception and behavior. Detailed descriptions are encouraged but enough introductory background should be included for non-specialists. Theoretical and computational papers should give a sense of order to the facts or point to new verifiable observations. Papers dealing with questions in the history of vision science should stress the development of ideas in the field.
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