溶酶体破坏了计算模拟微生物群的稳定性

IF 7.6 1区 环境科学与生态学 Q1 ECOLOGY
Ecology Letters Pub Date : 2024-06-22 DOI:10.1111/ele.14464
R. Tucker Gilman, Mark R. Muldoon, Spyridon Megremis, David L. Robertson, Nina Chanishvili, Nikolaos G. Papadopoulos
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引用次数: 0

摘要

微生物群是一个生态系统,其稳定性会影响宿主的健康。理论预测,捕食者会影响生态系统的稳定性。噬菌体是微生物群落中细菌的主要捕食者,但噬菌体是不寻常的捕食者,因为许多噬菌体的生命周期是溶解性的。据推测,溶菌作用会破坏微生物群的稳定性,但溶菌作用在经典生态学理论中并没有直接的对应物,也不存在正式的理论。我们研究了具有不同数量的温和性(溶解性)和毒性(强制性溶解性)噬菌体的计算模拟微生物组的稳定性。当温性噬菌体种类较多时,细菌种群更容易随时间波动。扰动后,当温带噬菌体种类较多时,细菌种群恢复到扰动前密度的速度较慢,但当毒性噬菌体种类较多时,扰动引起的周期减弱速度较慢。我们的研究首次提出了将溶菌作用与微生物群稳定性联系起来的正式理论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Lysogeny destabilizes computationally simulated microbiomes

Lysogeny destabilizes computationally simulated microbiomes

Microbiomes are ecosystems, and their stability can impact the health of their hosts. Theory predicts that predators influence ecosystem stability. Phages are key predators of bacteria in microbiomes, but phages are unusual predators because many have lysogenic life cycles. It has been hypothesized that lysogeny can destabilize microbiomes, but lysogeny has no direct analog in classical ecological theory, and no formal theory exists. We studied the stability of computationally simulated microbiomes with different numbers of temperate (lysogenic) and virulent (obligate lytic) phage species. Bacterial populations were more likely to fluctuate over time when there were more temperate phages species. After disturbances, bacterial populations returned to their pre-disturbance densities more slowly when there were more temperate phage species, but cycles engendered by disturbances dampened more slowly when there were more virulent phage species. Our work offers the first formal theory linking lysogeny to microbiome stability.

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来源期刊
Ecology Letters
Ecology Letters 环境科学-生态学
CiteScore
17.60
自引率
3.40%
发文量
201
审稿时长
1.8 months
期刊介绍: Ecology Letters serves as a platform for the rapid publication of innovative research in ecology. It considers manuscripts across all taxa, biomes, and geographic regions, prioritizing papers that investigate clearly stated hypotheses. The journal publishes concise papers of high originality and general interest, contributing to new developments in ecology. Purely descriptive papers and those that only confirm or extend previous results are discouraged.
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