John E. Rubin , Vanessa Ng , Justin Chung , Nicolas Salvatierra , Brady Rippon , Diana Khatib , Natalia I. Girardi , Kane O. Pryor , Roniel Y. Weinberg , Silis Jiang , Sherif Khairallah , Stephanie L. Mick , Tiffany R. Tedore
{"title":"胸骨正中切开术中胸骨旁周围神经导管与无阻滞的疗效对比:一项单中心回顾性研究","authors":"John E. Rubin , Vanessa Ng , Justin Chung , Nicolas Salvatierra , Brady Rippon , Diana Khatib , Natalia I. Girardi , Kane O. Pryor , Roniel Y. Weinberg , Silis Jiang , Sherif Khairallah , Stephanie L. Mick , Tiffany R. Tedore","doi":"10.1016/j.bjao.2024.100288","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Sternal pain after cardiac surgery results in considerable discomfort. Single-injection parasternal fascial plane blocks have been shown to reduce pain scores and opioid consumption during the first 24 h after surgery, but the efficacy of continuous infusion has not been evaluated. This retrospective cohort study examined the effect of a continuous infusion of local anaesthetic through parasternal catheters on the integrated Pain Intensity and Opioid Consumption (PIOC) score up to 72 h.</p></div><div><h3>Methods</h3><p>We performed a retrospective analysis of patients undergoing cardiac surgery with median sternotomy at a single academic centre before and after the addition of parasternal nerve catheters to a standard multimodal analgesic protocol. Outcomes included PIOC score, total opioid consumption in oral morphine equivalents, and time-weighted area under the curve pain scores up to 72 h after surgery.</p></div><div><h3>Results</h3><p>Continuous infusion of ropivacaine 0.1% through parasternal catheters resulted in a significant reduction in PIOC scores at 24 h (−62, 95% confidence interval −108 to −16; <em>P</em><0.01) and 48 h (−50, 95% CI −97 to −2.2; <em>P</em>=0.04) compared with no block. A significant reduction in opioid consumption up to 72 h was the primary factor in reduction of PIOC.</p></div><div><h3>Conclusions</h3><p>This study suggests that continuous infusion of local anaesthetic through parasternal catheters may be a useful addition to a multimodal analgesic protocol in patients undergoing cardiac surgery with sternotomy. Further prospective study is warranted to determine the full benefits of continuous infusion compared with single injection or no block.</p></div>","PeriodicalId":72418,"journal":{"name":"BJA open","volume":"11 ","pages":"Article 100288"},"PeriodicalIF":0.0000,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772609624000327/pdfft?md5=b2dc117c938cb27a0cec1461b69ab4f9&pid=1-s2.0-S2772609624000327-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Efficacy of parasternal peripheral nerve catheters versus no block for median sternotomy: a single-centre retrospective study\",\"authors\":\"John E. Rubin , Vanessa Ng , Justin Chung , Nicolas Salvatierra , Brady Rippon , Diana Khatib , Natalia I. Girardi , Kane O. Pryor , Roniel Y. Weinberg , Silis Jiang , Sherif Khairallah , Stephanie L. Mick , Tiffany R. Tedore\",\"doi\":\"10.1016/j.bjao.2024.100288\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Sternal pain after cardiac surgery results in considerable discomfort. Single-injection parasternal fascial plane blocks have been shown to reduce pain scores and opioid consumption during the first 24 h after surgery, but the efficacy of continuous infusion has not been evaluated. This retrospective cohort study examined the effect of a continuous infusion of local anaesthetic through parasternal catheters on the integrated Pain Intensity and Opioid Consumption (PIOC) score up to 72 h.</p></div><div><h3>Methods</h3><p>We performed a retrospective analysis of patients undergoing cardiac surgery with median sternotomy at a single academic centre before and after the addition of parasternal nerve catheters to a standard multimodal analgesic protocol. Outcomes included PIOC score, total opioid consumption in oral morphine equivalents, and time-weighted area under the curve pain scores up to 72 h after surgery.</p></div><div><h3>Results</h3><p>Continuous infusion of ropivacaine 0.1% through parasternal catheters resulted in a significant reduction in PIOC scores at 24 h (−62, 95% confidence interval −108 to −16; <em>P</em><0.01) and 48 h (−50, 95% CI −97 to −2.2; <em>P</em>=0.04) compared with no block. A significant reduction in opioid consumption up to 72 h was the primary factor in reduction of PIOC.</p></div><div><h3>Conclusions</h3><p>This study suggests that continuous infusion of local anaesthetic through parasternal catheters may be a useful addition to a multimodal analgesic protocol in patients undergoing cardiac surgery with sternotomy. Further prospective study is warranted to determine the full benefits of continuous infusion compared with single injection or no block.</p></div>\",\"PeriodicalId\":72418,\"journal\":{\"name\":\"BJA open\",\"volume\":\"11 \",\"pages\":\"Article 100288\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2772609624000327/pdfft?md5=b2dc117c938cb27a0cec1461b69ab4f9&pid=1-s2.0-S2772609624000327-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BJA open\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772609624000327\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BJA open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772609624000327","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Efficacy of parasternal peripheral nerve catheters versus no block for median sternotomy: a single-centre retrospective study
Background
Sternal pain after cardiac surgery results in considerable discomfort. Single-injection parasternal fascial plane blocks have been shown to reduce pain scores and opioid consumption during the first 24 h after surgery, but the efficacy of continuous infusion has not been evaluated. This retrospective cohort study examined the effect of a continuous infusion of local anaesthetic through parasternal catheters on the integrated Pain Intensity and Opioid Consumption (PIOC) score up to 72 h.
Methods
We performed a retrospective analysis of patients undergoing cardiac surgery with median sternotomy at a single academic centre before and after the addition of parasternal nerve catheters to a standard multimodal analgesic protocol. Outcomes included PIOC score, total opioid consumption in oral morphine equivalents, and time-weighted area under the curve pain scores up to 72 h after surgery.
Results
Continuous infusion of ropivacaine 0.1% through parasternal catheters resulted in a significant reduction in PIOC scores at 24 h (−62, 95% confidence interval −108 to −16; P<0.01) and 48 h (−50, 95% CI −97 to −2.2; P=0.04) compared with no block. A significant reduction in opioid consumption up to 72 h was the primary factor in reduction of PIOC.
Conclusions
This study suggests that continuous infusion of local anaesthetic through parasternal catheters may be a useful addition to a multimodal analgesic protocol in patients undergoing cardiac surgery with sternotomy. Further prospective study is warranted to determine the full benefits of continuous infusion compared with single injection or no block.