肌动蛋白皮层的第三个维度

IF 6 2区生物学 Q1 CELL BIOLOGY

Current Opinion in Cell Biology Pub Date : 2024-06-20 DOI:10.1016/j.ceb.2024.102381

Anumita Jawahar , Joseph Vermeil , Julien Heuvingh , Olivia du Roure , Matthieu Piel

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引用次数: 0

摘要

肌动蛋白皮层通常被描述为质膜下的一层薄薄的二维肌动蛋白丝，现在人们开始认识到它是一种更具活力的三维复合材料的一部分。在这篇综述中，我们将重点讨论构成肌动蛋白皮层三维结构的要素。我们还认为，丝状体和应力纤维等富含肌动蛋白的结构可被视为三维肌动蛋白皮层的专门组成部分。这拓宽了我们对皮层的定义，不再将其简化为一层薄薄的二维肌动蛋白丝。

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The third dimension of the actin cortex

The actin cortex, commonly described as a thin 2-dimensional layer of actin filaments beneath the plasma membrane, is beginning to be recognized as part of a more dynamic and three-dimensional composite material. In this review, we focus on the elements that contribute to the three-dimensional architecture of the actin cortex. We also argue that actin-rich structures such as filopodia and stress fibers can be viewed as specialized integral parts of the 3D actin cortex. This broadens our definition of the cortex, shifting from its simplified characterization as a thin, two-dimensional layer of actin filaments.

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来源期刊

Current Opinion in Cell Biology 生物-细胞生物学

CiteScore

14.60

自引率

1.30%

发文量

审稿时长

93 days

期刊介绍： Current Opinion in Cell Biology (COCEBI) is a highly respected journal that specializes in publishing authoritative, comprehensive, and systematic reviews in the field of cell biology. The journal's primary aim is to provide a clear and readable synthesis of the latest advances in cell biology, helping specialists stay current with the rapidly evolving field. Expert authors contribute to the journal by annotating and highlighting the most significant papers from the extensive body of research published annually, offering valuable insights and saving time for readers by distilling key findings. COCEBI is part of the Current Opinion and Research (CO+RE) suite of journals, which leverages the legacy of editorial excellence, high impact, and global reach to ensure that the journal is a widely read resource integral to scientists' workflow. It is published by Elsevier, a publisher known for its commitment to excellence in scientific publishing and the communication of reproducible biomedical research aimed at improving human health. The journal's content is designed to be an invaluable resource for a diverse audience, including researchers, lecturers, teachers, professionals, policymakers, and students.