Cladosporium xylophilum 真菌的次级代谢物。

IF 1.3 3区医学 Q3 CHEMISTRY, APPLIED

Journal of Asian Natural Products Research Pub Date : 2024-06-19 DOI:10.1080/10286020.2024.2362384

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引用次数: 0

摘要

研究人员从木霉（Cladosporium xylophilum）的稻米发酵中分离出了一种新的木霉醇衍生物 xylophilum A（1）以及 10 种已知化合物（2-11）。通过大量的光谱方法以及核磁共振数据与文献的比较，确定了这些化合物的结构。评估了化合物 1 对 11 种病原微生物的抗菌活性，但没有发现明显的活性（MIC >100 μg/ml）。

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Secondary metabolites from the fungus Cladosporium xylophilum

A new cladosporol derivative xylophilum A (1), together with 10 known compounds (2–11), were isolated from the rice fermentation of the fungus Cladosporium xylophilum. Their structures were established by extensive spectroscopic methods and comparison of their NMR data with literatures. The antimicrobial activity of compound 1 against 11 kinds of pathogenic microbial was evaluated, but no significant activity was found (MIC >100 μg/ml).

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来源期刊

Journal of Asian Natural Products Research 医学-药学

CiteScore

3.20

自引率

5.90%

发文量

审稿时长

2.3 months

期刊介绍： The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.