一种来自 Ochrocarpus longifolius 的新香豆素和一种新黄酮类化合物。

IF 1.3 3区医学 Q3 CHEMISTRY, APPLIED

Journal of Asian Natural Products Research Pub Date : 2024-06-19 DOI:10.1080/10286020.2024.2363416

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引用次数: 0

摘要

从 Ochrocarpus longifolius 的风干花蕾中分离出了一种新的香豆素（1）和一种新的黄酮类化合物（2），以及十种已知化合物（3-12）。通过一维、二维核磁共振和质谱数据，确定了两种新化合物的结构。此外，新化合物 2 对 Eca-109 和 MGC-803 细胞具有显著的增殖抑制活性。本研究的结果可能会丰富长叶乌头的化合物多样性，并为进一步研究其天然产物和药理活性提供依据。

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A new coumarin and a new flavonoid from Ochrocarpus longifolius

A new coumarin (1) and a new flavonoid (2) were isolated from the air-dried flower buds of Ochrocarpus longifolius, together with ten known compounds (3–12). The structures of two new compounds were established by 1D and 2D NMR and MS data. In addition, the new compound 2 showed significant proliferation inhibitory activity on Eca-109 and MGC-803 cells. The results of this study may enrich the diversity of compounds from O. longifolius and provide a basis for further research on its natural products and pharmacological activities.

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来源期刊

Journal of Asian Natural Products Research 医学-药学

CiteScore

3.20

自引率

5.90%

发文量

审稿时长

2.3 months

期刊介绍： The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.