Jing Luo, Rui Xie, Chongxi Bao, Jinyan Lin, Yang Xu, Xuexin Yan, Zhen Yang, Li Feng, Jianing Wu, Dan Chen, Zaiqing He, Jinliang Kong
{"title":"分析携带人类疱疹病毒患者的肺部微生态学和临床特征。","authors":"Jing Luo, Rui Xie, Chongxi Bao, Jinyan Lin, Yang Xu, Xuexin Yan, Zhen Yang, Li Feng, Jianing Wu, Dan Chen, Zaiqing He, Jinliang Kong","doi":"10.1080/17460913.2024.2357994","DOIUrl":null,"url":null,"abstract":"<p><p><b>Aim:</b> To investigate the impact of human herpes virus (<i>HHV</i>) carriage on lung microbiota, and its correlation with clinical features and laboratory indicators in patients.<b>Methods:</b> Retrospective analysis was conducted on 30 outpatient lung infection cases, which were divided into <i>HHV</i> (n = 15) and non-<i>HHV</i> (n = 15) groups. mNGS detected microbial composition. Microbial diversity and abundance were tested using Shannon and Chao1 indices. Their relationship with laboratory indicators were explored.<b>Results:</b> Significant differences in microbial abundance and distribution were found between two groups (p < 0.05). Moreover, HHV group showed negative correlations (p < 0.05) between <i>Prevotella</i>, <i>Porphyromonas</i>, <i>Streptococcus</i> and basophil/eosinophil percentages.<b>Conclusion:</b> <i>HHV</i> carriage impacts lung microbiota, emphasizing the need for clinicians to pay attention to <i>HHV</i> reactivation in outpatient lung infection patients.</p>","PeriodicalId":12773,"journal":{"name":"Future microbiology","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11323855/pdf/","citationCount":"0","resultStr":"{\"title\":\"Analysis of pulmonary microecology and clinical characteristics of patients carrying human herpesvirus.\",\"authors\":\"Jing Luo, Rui Xie, Chongxi Bao, Jinyan Lin, Yang Xu, Xuexin Yan, Zhen Yang, Li Feng, Jianing Wu, Dan Chen, Zaiqing He, Jinliang Kong\",\"doi\":\"10.1080/17460913.2024.2357994\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Aim:</b> To investigate the impact of human herpes virus (<i>HHV</i>) carriage on lung microbiota, and its correlation with clinical features and laboratory indicators in patients.<b>Methods:</b> Retrospective analysis was conducted on 30 outpatient lung infection cases, which were divided into <i>HHV</i> (n = 15) and non-<i>HHV</i> (n = 15) groups. mNGS detected microbial composition. Microbial diversity and abundance were tested using Shannon and Chao1 indices. Their relationship with laboratory indicators were explored.<b>Results:</b> Significant differences in microbial abundance and distribution were found between two groups (p < 0.05). Moreover, HHV group showed negative correlations (p < 0.05) between <i>Prevotella</i>, <i>Porphyromonas</i>, <i>Streptococcus</i> and basophil/eosinophil percentages.<b>Conclusion:</b> <i>HHV</i> carriage impacts lung microbiota, emphasizing the need for clinicians to pay attention to <i>HHV</i> reactivation in outpatient lung infection patients.</p>\",\"PeriodicalId\":12773,\"journal\":{\"name\":\"Future microbiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2024-08-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11323855/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Future microbiology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1080/17460913.2024.2357994\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/6/20 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future microbiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1080/17460913.2024.2357994","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/20 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
Analysis of pulmonary microecology and clinical characteristics of patients carrying human herpesvirus.
Aim: To investigate the impact of human herpes virus (HHV) carriage on lung microbiota, and its correlation with clinical features and laboratory indicators in patients.Methods: Retrospective analysis was conducted on 30 outpatient lung infection cases, which were divided into HHV (n = 15) and non-HHV (n = 15) groups. mNGS detected microbial composition. Microbial diversity and abundance were tested using Shannon and Chao1 indices. Their relationship with laboratory indicators were explored.Results: Significant differences in microbial abundance and distribution were found between two groups (p < 0.05). Moreover, HHV group showed negative correlations (p < 0.05) between Prevotella, Porphyromonas, Streptococcus and basophil/eosinophil percentages.Conclusion:HHV carriage impacts lung microbiota, emphasizing the need for clinicians to pay attention to HHV reactivation in outpatient lung infection patients.
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Future Microbiology delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this increasingly important and vast area of research.
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