封面内页:光声成像引导下的超分子酞菁组装体--增强型协同光动力和光热疗法

IF 13.9 Q1 CHEMISTRY, MULTIDISCIPLINARY
Yuan-Yuan Zhao, Xiaojun Zhang, Zixuan Chen, Yihui Xu, Heejeong Kim, Hyunsun Jeong, You Rim Lee, Jiah Lee, Xingshu Li, Juyoung Yoon
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引用次数: 0

摘要

在这项工作中,Yoon 及其合作者开发了一种基于佛斯特共振能量转移机制的纳米结构超分子光治疗剂。这种纳米结构的光治疗剂能使肿瘤可视化,光声信号与肝脏的比值高达 11.9,并通过光动力和光热协同疗法,最终在临床前模型中以低剂量实现了显著的治疗效果 (e514)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Inside Front Cover: Supramolecular phthalocyanine assemblies-enhanced synergistic photodynamic and photothermal therapy guided by photoacoustic imaging

Inside Front Cover: Supramolecular phthalocyanine assemblies-enhanced synergistic photodynamic and photothermal therapy guided by photoacoustic imaging

In this work, Yoon and co-workers developed a nanostructured supramolecular phototherapeutic agent based on Förster resonance energy transfer mechanism. Such nanostructured phototherapeutic agent can enable the visualization of a tumor with a photoacoustic signal-to-liver ratio as high as 11.9, and ultimately achieving a notable therapeutic effect in a preclinical model at a low dose through the photodynamic and photothermal synergistic therapy (e514).

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CiteScore
17.40
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