Yuan-Yuan Zhao, Xiaojun Zhang, Zixuan Chen, Yihui Xu, Heejeong Kim, Hyunsun Jeong, You Rim Lee, Jiah Lee, Xingshu Li, Juyoung Yoon
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Inside Front Cover: Supramolecular phthalocyanine assemblies-enhanced synergistic photodynamic and photothermal therapy guided by photoacoustic imaging
In this work, Yoon and co-workers developed a nanostructured supramolecular phototherapeutic agent based on Förster resonance energy transfer mechanism. Such nanostructured phototherapeutic agent can enable the visualization of a tumor with a photoacoustic signal-to-liver ratio as high as 11.9, and ultimately achieving a notable therapeutic effect in a preclinical model at a low dose through the photodynamic and photothermal synergistic therapy (e514).
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