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卵巢母体水凝胶的异质性阐明了可能影响体外卵泡生长的因素

IF 3.7 3区 生物学 Q1 DEVELOPMENTAL BIOLOGY
Reproduction Pub Date : 2024-08-22 Print Date: 2024-09-01 DOI:10.1530/REP-24-0135
Hannah B McDowell, Nathaniel F Henning, Monica M Laronda
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引用次数: 0

摘要

这项工作描述了一种宝贵的、可重复的方法，用于生成支持体外小鼠卵泡生长的光学透明牛卵巢衍生水凝胶。这些技术是将卵泡生长动态与基质蛋白组成相关联以揭示这些蛋白质在卵泡生成中的作用的基础。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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Heterogeneity of ovarian matrisome hydrogels elucidates factors that may influence follicle growth in vitro.

This work describes a valuable and reproducible method for generating optically clear bovine ovary-derived hydrogels that support in vitro murine follicle growth. These techniques are the foundation in which follicle growth dynamics and matrisome protein composition may be correlated to reveal the influence of matrisome proteins on folliculogenesis.

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来源期刊
Reproduction
Reproduction 生物-发育生物学
CiteScore
7.40
自引率
2.60%
发文量
199
审稿时长
4-8 weeks
期刊介绍： Reproduction is the official journal of the Society of Reproduction and Fertility (SRF). It was formed in 2001 when the Society merged its two journals, the Journal of Reproduction and Fertility and Reviews of Reproduction. Reproduction publishes original research articles and topical reviews on the subject of reproductive and developmental biology, and reproductive medicine. The journal will consider publication of high-quality meta-analyses; these should be submitted to the research papers category. The journal considers studies in humans and all animal species, and will publish clinical studies if they advance our understanding of the underlying causes and/or mechanisms of disease. Scientific excellence and broad interest to our readership are the most important criteria during the peer review process. The journal publishes articles that make a clear advance in the field, whether of mechanistic, descriptive or technical focus. Articles that substantiate new or controversial reports are welcomed if they are noteworthy and advance the field. Topics include, but are not limited to, reproductive immunology, reproductive toxicology, stem cells, environmental effects on reproductive potential and health (eg obesity), extracellular vesicles, fertility preservation and epigenetic effects on reproductive and developmental processes.
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