假体周围关节感染研究中的性别差异。

IF 1.8 Q3 INFECTIOUS DISEASES
Journal of Bone and Joint Infection Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI:10.5194/jbji-9-137-2024
Domenico De Mauro, Cesare Meschini, Giovanni Balato, Tiziana Ascione, Enrico Festa, Davide Bizzoca, Biagio Moretti, Giulio Maccauro, Raffaele Vitiello
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引用次数: 0

摘要

导言:假体周围关节感染(PJIs)已成为骨科领域的一个焦点,由于其发病率不断攀升以及对接受全关节置换术(TJA)的患者造成的深远影响,PJIs 引起了广泛关注。年复一年,该领域对多种风险因素、并发症发生率和手术治疗方法的分析呈增长趋势。本研究旨在阐明假体周围关节感染中与性别相关的差异,并推动该领域的研究。研究方法按照《系统综述和元分析首选报告项目》(PRISMA)指南进行了系统综述。最终的参考文献列表包括纵向研究(包括回顾性研究和前瞻性研究)和随机对照试验。还进行了基于性别的分析,以评估男性和女性之间的差异。结果通过在线数据库搜索和参考文献调查,共初步确定了 312 项研究。随后,9 项研究被纳入审查范围。九项研究中有八项研究了全关节置换术后患 PJI 的风险。值得注意的是,其中只有半数研究的P值为0.05,表明男性感染并发症的风险高于女性。结论:根据目前的文献,男性在全关节置换术后发生假体周围关节感染的几率似乎高于女性。要收集更有力的证据和见解,加强该领域的性别相关分析势在必行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sex-related differences in periprosthetic joint infection research.

Introduction: Periprosthetic joint infections (PJIs) have emerged as a focal point in the realm of orthopedics, garnering widespread attention owing to the escalating incidence rates and the profound impact they impose on patients undergoing total joint arthroplasties (TJAs). Year after year, there has been a growing trend in the analysis of multiple risk factors, complication rates, and surgical treatments in the field. This study aims to illuminate the status of the sex-related differences in periprosthetic joint infections and advance research in this field. Methods: A systematic review was carried out following the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. The final reference list comprised longitudinal studies (both retrospective and prospective) and randomized controlled trials. A sex-based analysis was conducted to assess differences between males and females. Results: A total of 312 studies were initially identified through online database searches and reference investigations. Nine studies were subsequently included in the review. Eight out of nine studies examined the risk of developing PJI after total joint replacement. Notably, only half of these studies demonstrated a statistically significant value, with a p  value  < 0.05 , indicating a higher risk of infectious complications in males compared to females. Conclusion: According to the current literature, there appears to be a propensity for males to develop periprosthetic joint infection after total joint arthroplasty at a higher rate than the female population. Enhancing sex-related analysis in this field is imperative for gathering more robust evidence and insights.

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来源期刊
CiteScore
3.70
自引率
0.00%
发文量
29
审稿时长
12 weeks
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